Physical Sciences and Mathematics Commons^™

Depth-Resolved Multispectral Sub-Surface Imaging Using Multifunctional Upconversion Phosphors With Paramagnetic Properties, Zaven Ovanesyan, L. Christopher Mimun, Gangadharan Ajith Kumar, Brian G. Yust, Chamath Dannongoda, Karen S. Martirosyan, Dhiraj K. Sardar

Physics and Astronomy Faculty Publications and Presentations

Molecular imaging is very promising technique used for surgical guidance, which requires advancements related to properties of imaging agents and subsequent data retrieval methods from measured multispectral images. In this article, an upconversion material is introduced for subsurface near-infrared imaging and for the depth recovery of the material embedded below the biological tissue. The results confirm significant correlation between the analytical depth estimate of the material under the tissue and the measured ratio of emitted light from the material at two different wavelengths. Experiments with biological tissue samples demonstrate depth resolved imaging using the rare earth doped multifunctional phosphors. In …