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Full-Text Articles in Physical Sciences and Mathematics
Pathological Comparisons Of The Hippocampal Changes In The Transient And Permanent Middle Cerebral Artery Occlusion Rat Models, Fawad Ali Shah, Tao Li, Lina Tariq Al Kury, Alam Zeb, Shehla Khatoon, Gongping Liu, Xifei Yang, Fang Liu, Huo Yao, Arif Ullah Khan, Phil Ok Koh, Yuhua Jiang, Shupeng Li
Pathological Comparisons Of The Hippocampal Changes In The Transient And Permanent Middle Cerebral Artery Occlusion Rat Models, Fawad Ali Shah, Tao Li, Lina Tariq Al Kury, Alam Zeb, Shehla Khatoon, Gongping Liu, Xifei Yang, Fang Liu, Huo Yao, Arif Ullah Khan, Phil Ok Koh, Yuhua Jiang, Shupeng Li
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© Copyright © 2019 Shah, Li, Kury, Zeb, Khatoon, Liu, Yang, Liu, Yao, Khan, Koh, Jiang and Li. Ischemic strokes are categorized by permanent or transient obstruction of blood flow, which impedes delivery of oxygen and essential nutrients to brain. In the last decade, the therapeutic window for tPA has increased from 3 to 5–6 h, and a new technique, involving the mechanical removal of the clot (endovascular thrombectomy) to allow reperfusion of the injured area, is being used more often. This last therapeutic approach can be done until 24 h after stroke onset. Due to this fact, more acute …
Regional Effects Of Streptozotocin-Induced Diabetes On Shortening And Calcium Transport In Epicardial And Endocardial Myocytes From Rat Left Ventricle, Manal M.A. Smaill, Muhammad A. Qureshi, Anatoliy Shmygol, Murat Oz, Jaipaul Singh, Vadym Sydorenko, Alya Arabi, Frank C. Howarth, Lina Al Kury
Regional Effects Of Streptozotocin-Induced Diabetes On Shortening And Calcium Transport In Epicardial And Endocardial Myocytes From Rat Left Ventricle, Manal M.A. Smaill, Muhammad A. Qureshi, Anatoliy Shmygol, Murat Oz, Jaipaul Singh, Vadym Sydorenko, Alya Arabi, Frank C. Howarth, Lina Al Kury
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© 2016 The Authors. In the heart, the left ventricle pumps blood at higher pressure than the right ventricle. Within the left ventricle, the electromechanical properties of ventricular cardiac myocytes vary transmurally and this may be related to the gradients of stress and strain experienced in vivo across the ventricular wall. Diabetes is also associated with alterations in hemodynamic function. The aim of this study was to investigate shortening and Ca2+ transport in epicardial (EPI) and endocardial (ENDO) left ventricular myocytes in the streptozotocin (STZ)-induced diabetic rat. Shortening, intracellular Ca2+ and L-type Ca2+ current (ICa,L) were measured by video detection, …