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Full-Text Articles in Physical Sciences and Mathematics

The Proliferation Of Vascular Smooth Muscle Cells Depends On Thioredoxin 1 Protein In A Model Of Pulmonary Hypertension, Viktoria Nelin May 2011

The Proliferation Of Vascular Smooth Muscle Cells Depends On Thioredoxin 1 Protein In A Model Of Pulmonary Hypertension, Viktoria Nelin

Mahurin Honors College Capstone Experience/Thesis Projects

Pulmonary hypertension (PH) is a disease which manifests itself in the lungs of both adults and children. Vascular proliferation and remodeling are the hallmarks of PH and are found mainly in the pulmonary arterial smooth muscle cells (PASMC). The cause of PASMC proliferation and vascular remodeling in PH is poorly understood. Hypoxia, or low oxygen content, underlies many forms of PH. Hypoxia results in alterations in the redox balance of the PASMC. Therefore, the aim of this study was to examine the role of the thioredoxin system, an antioxidant system in the cell, in hypoxia-induced proliferation in PASMC. Protein was …


Assessment Of Prenatal Care And Perinatal Outcomes In Kasigau, Kenya, Allison Smith May 2011

Assessment Of Prenatal Care And Perinatal Outcomes In Kasigau, Kenya, Allison Smith

Mahurin Honors College Capstone Experience/Thesis Projects

The World Health Organization (WHO) implemented the Millennium Declaration in 2000 to establish global health goals to be achieved by 2015. Two of these Millennium Development Goals (MDG’s) are directly related to maternal, neonatal and child health. Healthcare during the prenatal period can help achieve the WHO MDG’s for maternal health and child mortality. Evidence has shown that women in Kenya have limited access to prenatal care. This study focused on the prenatal care and postnatal outcome trends of the women in Kasigau, Kenya. Participants were surveyed in three villages (Rukanga, Makwasinyi, and Bhuguta) to determine if prenatal care was …