Physical Sciences and Mathematics Commons^™

Additive And Multiplicative Hazards Modeling For Recurrent Event Data Analysis, Hyun J. Lim, Xu Zhang

Mathematics and Statistics Faculty Publications

Background: Sequentially ordered multivariate failure time or recurrent event duration data are commonly observed in biomedical longitudinal studies. In general, standard hazard regression methods cannot be applied because of correlation between recurrent failure times within a subject and induced dependent censoring. Multiplicative and additive hazards models provide the two principal frameworks for studying the association between risk factors and recurrent event durations for the analysis of multivariate failure time data.

Methods: Using emergency department visits data, we illustrated and compared the additive and multiplicative hazards models for analysis of recurrent event durations under (i) a varying baseline with a common …