Physical Sciences and Mathematics Commons^™

A Tutorial On Radiation Oncology And Optimization, Allen G. Holder, Bill Salter

Mathematics Faculty Research

Designing radiotherapy treatments is a complicated and important task that affects patient care, and modern delivery systems enable a physician more flexibility than can be considered. Consequently, treatment design is increasingly automated by techniques of optimization, and many of the advances in the design process are accomplished by a collaboration among medical physicists, radiation oncologists, and experts in optimization. This tutorial is meant to aid those with a background in optimization in learning about treatment design. Besides discussing several optimization models, we include a clinical perspective so that readers understand the clinical issues that are often ignored in the optimization …