Physical Sciences and Mathematics | Open Access Articles

Comparative Survival Of Asian And White Metastatic Castration-Resistant Prostate Cancer Men Treated With Docetaxel, Susan Halabi, Sandipan Dutta, Catherine M. Tangen, Mark Rosenthal, Daniel P. Petrylak, Ian M. Thompson Jr., Kim N. Chi, Johann S. De Bono, John C. Araujo, Christopher Logothetis, Mario A. Eisenberger, David I. Quinn, Karim Fizazi, Michael J. Morris, Celestia S. Higano, Ian F. Tannock, Eric J. Small, William Kevin Kelly

Mathematics & Statistics Faculty Publications

There are few data regarding disparities in overall survival (OS) between Asian and white men with metastatic castration-resistant prostate cancer (mCRPC). We compared OS of Asian and white mCRPC men treated in phase III clinical trials with docetaxel and prednisone (DP) or a DP-containing regimen. Individual participant data from 8820 men with mCRPC randomly assigned on nine phase III trials to receive DP or a DP-containing regimen were combined. Men enrolled in these trials had a diagnosis of prostate adenocarcinoma. The median overall survival was 18.8 months (95% confidence interval [CI] = 17.4 to 22.1 months) and 21.2 months (95% …

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Investigating The Numerical Stability Of Using An Impedance Boundary Condition To Model Broadband Noise Scattering With Acoustic Liners, Michelle E. Rodio, Fang Q. Hu, Douglas M. Nark

Mathematics & Statistics Faculty Publications

Reducing aircraft noise is a major objective in the field of computational aeroacoustics. When designing next generation quiet aircraft, it is important to be able to accurately and efficiently predict the acoustic scattering by an aircraft body from a given noise source. Acoustic liners are an effective tool for achieving aircraft noise reduction and are characterized by a frequency-dependent impedance value. Converted into the time-domain using Fourier transforms, an impedance boundary condition can be used to simulate the acoustic wave scattering by geometric bodies treated with acoustic liners. A Broadband Impedance Model will be discussed in which the liner impedance …

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Classification Models Of Idiopathic Pulmonary Fibrosis Patients, Mohammed Alqawba, Luis R. Rodriguez, Norou Diawara, Rebecca T. Beuschel, Maryann Kaler, Amisha V. Barochia, Stewart J. Levine, Steven D. Nathan, Geraldine Grant

Mathematics & Statistics Faculty Publications

Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal interstitial lung disease with no current cure. Progression of IPF is difficult to predict as the clinical course can be highly variable and range from a rapidly deteriorating state to a relatively stable state, or may be characterized by a slow progressive decline. Therefore, the need for an accurate diagnosis and improved tools for monitoring and managing IPF is of paramount importance, all for understanding the mitochondrial structure and the function played in the IPF. Mitochondrial DNA copy number (MtDCN) has been correlated with mortality in IPF patients and is a …

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Computing The Newton Potential In The Boundary Integral Equation For The Dirichlet Problem Of The Poisson Equation, Wenchao Guan, Ying Jiang, Yuesheng Xu

Mathematics & Statistics Faculty Publications

Evaluating the Newton potential is crucial for efficiently solving the boundary integral equation of the Dirichlet boundary value problem of the Poisson equation. In the context of the Fourier-Garlerkin method for solving the boundary integral equation, we propose a fast algorithm for evaluating Fourier coefficients of the Newton potential by using a sparse grid approximation. When the forcing function of the Poisson equation expressed in the polar coordinates has mth-order bounded mixed derivatives, the proposed algorithm achieves an accuracy of order 𝒪(n^-m log³ n), with requiring 𝒪(n log² n) number of arithmetics for …

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Teacher Support Of Co- And Socially-Shared Regulation Of Learning In Middle School Mathematics Classrooms, Melissa Quackenbush, Linda Bol

Educational Foundations & Leadership Faculty Publications

Social influences on classroom learning have a long research tradition and are critical components of self-regulated learning theories. More recently, researchers have explored the social influences of self-regulated learning in cooperative learning contexts. In these settings, co-regulation of learning and socially-shared regulation of learning strategies have been aligned with self-regulated learning theory. However, without specific training or structure, teachers are not likely to explicitly integrate SRL strategies into their teaching. We use case studies to better understand how Zimmerman's theory of self-regulated learning (2008) and Hadwin's conceptual framework of socially-shared regulation of learning (2018) emerge from teachers' support of student-centered …

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Psu At Clef-2020 Arqmath Track: Unsupervised Re-Ranking Using Pretraining, Shaurya Rohatgi, Jian Wu, C. Lee Giles

Computer Science Faculty Publications

This paper elaborates on our submission to the ARQMath track at CLEF 2020. Our primary run for the main Task-1: Question Answering uses a two-stage retrieval technique in which the first stage is a fusion of traditional BM25 scoring and tf-idf with cosine similarity-based retrieval while the second stage is a finer re-ranking technique using contextualized embeddings. For the re-ranking we use a pre-trained robertabase model (110 million parameters) to make the language model more math-aware. Our approach achieves a higher NDCG0 score than the baseline, while our MAP and P@10 scores are competitive, performing better than the best submission …

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Numerical Modeling Of Submicron Particles For Acoustic Concentration In Gaseous Flow, Jizhou Liu, Xiaodong Li, Fang Q. Hu

Mathematics & Statistics Faculty Publications

This paper intends to explore the rationality and feasibility of modeling dispersed submicron particles in air by a kinetic-based method called the unified gas-kinetic scheme (UGKS) and apply it to the simulation of particle concentration under a transverse standing wave. A gas-particle coupling scheme is proposed where the gas phase is modeled by the two-dimensional linearized Euler equations (LEE) and, through the analogous behavior between the rarefied gas molecules and the air-suspended particles, a modified UGKS is adopted to estimate the particle dynamics. The Stokes' drag force and the acoustic radiation force applied on particles are accounted for by introducing …

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Residual Control Chart For Binary Response With Multicollinearity Covariates By Neural Network Model, Jong-Min Kim, Ning Wang, Yumin Liu, Kayoung Park

Mathematics & Statistics Faculty Publications

Quality control studies have dealt with symmetrical data having the same shape with respect to left and right. In this research, we propose the residual (r) control chart for binary asymmetrical (non-symmetric) data with multicollinearity between input variables via combining principal component analysis (PCA), functional PCA (FPCA) and the generalized linear model with probit and logit link functions, and neural network regression model. The motivation in this research is that the proposed control chart method can deal with both high-dimensional correlated multivariate data and high frequency functional multivariate data by neural network model and FPCA. We show that the neural …

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What's Your Sphericity Index? Rationalizing Surface Area And Volume, John A. Adam

Mathematics & Statistics Faculty Publications

Virginia Standards of Learning include mathematical content related to the surface area and the volume of various geometric objects. In the seventh grade, “Students... solve problems involving volume and surface area” In the eighth grade, “Proportional reasoning is expounded upon as students solve a variety of problems. Students find the volume and surface area of more complex three dimensional figures”. In high school geometry, “The student... use[s] surface area and volume of three-dimensional objects to solve practical problems” (Virginia Department of Education, 2016). The challenge is to find scenarios that are engaging to students and keep them interested in the …

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Quantifying The Varying Predictive Value Of Physical Activity Measures Obtained From Wearable Accelerometers On All-Cause Mortality Over Short To Medium Time Horizons In Nhanes 2003-2006, Lucia Tabacu, Mark Ledbetter, Andrew Leroux, Ciprian Crainiceanu, Ekaterina Smirnova

Mathematics & Statistics Faculty Publications

Physical activity measures derived from wearable accelerometers have been shown to be highly predictive of all-cause mortality. Prediction models based on traditional risk factors and accelerometry-derived physical activity measures are developed for five time horizons. The data set contains 2978 study participants between 50 and 85 years old with an average of 13.08 years of follow-up in the NHANES 2003–2004 and 2005–2006. Univariate and multivariate logistic regression models were fit separately for five datasets for one- to five-year all-cause mortality as outcome (number of events 46, 94, 155, 218, and 297, respectively). In univariate models the total activity count (TAC) …

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Multiplicative Noise Removal: Nonlocal Low-Rank Model And It's Proximal Alternating Reweighted Minimization Algorithm, Xiaoxia Liu, Jian Lu, Lixin Shen, Chen Xu, Yuesheng Xu

Mathematics & Statistics Faculty Publications

The goal of this paper is to develop a novel numerical method for efficient multiplicative noise removal. The nonlocal self-similarity of natural images implies that the matrices formed by their nonlocal similar patches are low-rank. By exploiting this low-rank prior with application to multiplicative noise removal, we propose a nonlocal low-rank model for this task and develop a proximal alternating reweighted minimization (PARM) algorithm to solve the optimization problem resulting from the model. Specifically, we utilize a generalized nonconvex surrogate of the rank function to regularize the patch matrices and develop a new nonlocal low-rank model, which is a nonconvex …

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Full-Text Articles in Physical Sciences and Mathematics

Mathematics & Statistics Faculty Publications

Investigating The Numerical Stability Of Using An Impedance Boundary Condition To Model Broadband Noise Scattering With Acoustic Liners, Michelle E. Rodio, Fang Q. Hu, Douglas M. Nark

Mathematics & Statistics Faculty Publications

Classification Models Of Idiopathic Pulmonary Fibrosis Patients, Mohammed Alqawba, Luis R. Rodriguez, Norou Diawara, Rebecca T. Beuschel, Maryann Kaler, Amisha V. Barochia, Stewart J. Levine, Steven D. Nathan, Geraldine Grant

Mathematics & Statistics Faculty Publications

Computing The Newton Potential In The Boundary Integral Equation For The Dirichlet Problem Of The Poisson Equation, Wenchao Guan, Ying Jiang, Yuesheng Xu

Mathematics & Statistics Faculty Publications

Teacher Support Of Co- And Socially-Shared Regulation Of Learning In Middle School Mathematics Classrooms, Melissa Quackenbush, Linda Bol

Educational Foundations & Leadership Faculty Publications

Psu At Clef-2020 Arqmath Track: Unsupervised Re-Ranking Using Pretraining, Shaurya Rohatgi, Jian Wu, C. Lee Giles

Computer Science Faculty Publications

Numerical Modeling Of Submicron Particles For Acoustic Concentration In Gaseous Flow, Jizhou Liu, Xiaodong Li, Fang Q. Hu

Mathematics & Statistics Faculty Publications

Residual Control Chart For Binary Response With Multicollinearity Covariates By Neural Network Model, Jong-Min Kim, Ning Wang, Yumin Liu, Kayoung Park

Mathematics & Statistics Faculty Publications

What's Your Sphericity Index? Rationalizing Surface Area And Volume, John A. Adam

Mathematics & Statistics Faculty Publications

Quantifying The Varying Predictive Value Of Physical Activity Measures Obtained From Wearable Accelerometers On All-Cause Mortality Over Short To Medium Time Horizons In Nhanes 2003-2006, Lucia Tabacu, Mark Ledbetter, Andrew Leroux, Ciprian Crainiceanu, Ekaterina Smirnova

Mathematics & Statistics Faculty Publications

Multiplicative Noise Removal: Nonlocal Low-Rank Model And It's Proximal Alternating Reweighted Minimization Algorithm, Xiaoxia Liu, Jian Lu, Lixin Shen, Chen Xu, Yuesheng Xu

Mathematics & Statistics Faculty Publications