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Full-Text Articles in Physical Sciences and Mathematics
Molecular Characterization And Expression Of Cytochrome P450 Aromatase In Atlantic Croaker Brain: Regulation By Antioxidant Status And Nitric Oxide Synthase During Hypoxia Stress, Md Saydur Rahman, Peter Thomas
Molecular Characterization And Expression Of Cytochrome P450 Aromatase In Atlantic Croaker Brain: Regulation By Antioxidant Status And Nitric Oxide Synthase During Hypoxia Stress, Md Saydur Rahman, Peter Thomas
School of Earth, Environmental, and Marine Sciences Faculty Publications and Presentations
We have previously shown that nitric oxide synthase (NOS, an enzyme) is significantly increased during hypoxic stress in Atlantic croaker brains and modulated by an antioxidant (AOX). However, the influence of NOS and AOX on cytochrome P450 aromatase (AROM, CYP19a1, an enzyme) activity on vertebrate brains during hypoxic stress is largely unknown. In this study, we characterized brain AROM (bAROM, CYP19a1b) cDNA in croaker and examined the interactive effects of hypoxia and a NOS-inhibitor or AOX on AROM activity. The amino acid sequence of croaker bAROM cDNA is highly homologous (76–80%) to other marine teleost bAROM cDNAs. Both real-time PCR …
Medical Schools Ignore The Nature Of Consciousness At Great Cost, Anoop Kumar
Medical Schools Ignore The Nature Of Consciousness At Great Cost, Anoop Kumar
Journal of Wellness
The essential question of the relationship between consciousness and matter is ignored in medical school curricula, leading to a machine-like view of the human being that contributes to physician burnout and intellectual dissatisfaction. The evidence suggesting that the brain may not be the seat of consciousness is generally ignored to preserve the worldview of the primacy of matter. By investigating new frameworks detailing the nature of consciousness at different levels of hierarchy, we can bring intellectual rigor to a once opaque subject that supports a fundamental reality about our experience: We are human beings, not only human bodies.