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Articles 1 - 16 of 16

Full-Text Articles in Physical Sciences and Mathematics

Membrane Lipid-Modulated Mechanism Of Action And Non-Cytotoxicity Of Novel Fungicide Aminoglycoside Fg08, Sanjib Shrestha, Michelle Grilley, Marina Y. Fosso, Cheng-Wei Tom Chang, Jon Y. Takemoto Sep 2013

Membrane Lipid-Modulated Mechanism Of Action And Non-Cytotoxicity Of Novel Fungicide Aminoglycoside Fg08, Sanjib Shrestha, Michelle Grilley, Marina Y. Fosso, Cheng-Wei Tom Chang, Jon Y. Takemoto

Chemistry and Biochemistry Faculty Publications

A novel aminoglycoside, FG08, that differs from kanamycin B only by a C8 alkyl chain at the 4″-O position, was previously reported. Unlike kanamycin B, FG08 shows broad-spectrum fungicidal but not anti-bacterial activities. To understand its specificity for fungi, the mechanism of action of FG08 was studied using intact cells of the yeast Saccharomyces cerevisiae and small unilamellar membrane vesicles. With exposure to FG08 (30 µg mL−1), 8-fold more cells were stained with fluorescein isothiocyanate, cells had 4 to 6-fold higher K+ efflux rates, and 18-fold more cells were stained with SYTOX Green in comparison to exposure to kanamycin B …


Modeling Habitat Use Of A Fringe Greater Sage-Grouse Population At Multiple Spatial Scales, Anya Cheyenne Burnett Aug 2013

Modeling Habitat Use Of A Fringe Greater Sage-Grouse Population At Multiple Spatial Scales, Anya Cheyenne Burnett

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Greater sage-grouse (Centrocercus urophasianus; hereafter sage-grouse) are a prominent bird species of sagebrush-dominated landscapes across the western United States. Over the past 15 years, sage-grouse have gained international attention due to decreasing population trends despite management efforts. In 2010 the U.S. Fish and Wildlife Service designated this species as warranted for listing under the Endangered Species Act, but the listing was precluded by other species at higher conservation risk. Habitat loss, degradation, and fragmentation have been implicated as primary sources of declines in sage-grouse distribution and abundance. The Bald Hills population in southwestern Utah occupies an area with …


Climate Change And Plant Demography In The Sagebrush Steppe, Aldo Compagnoni Jul 2013

Climate Change And Plant Demography In The Sagebrush Steppe, Aldo Compagnoni

Green Canyon Environmental Research Area, Logan Utah

No abstract provided.


Effect Of Step Rate On Foot Strike Pattern And Running Economy In Novice Runners, Janae Lynn Richardson May 2013

Effect Of Step Rate On Foot Strike Pattern And Running Economy In Novice Runners, Janae Lynn Richardson

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Purpose—The objective was to examine if step rates ±5% or ±10% of a novice runner's preferred step rate (SR) is sufficient enough to shift a novice runner’s foot strike pattern (FSP) (rear-foot, mid-foot, forefoot) and whether these SR changes produce changes in the rate of submaximal oxygen consumption (VO2). Methods—Foot strike angle (FSA) was recorded using sagittal plane video images and VO2 was measured for novice runners while running on a treadmill at a constant speed during increased and decreased (±5% and ±10%) SR conditions. Foot strike angle was used to predict strike index (SI) (predicted strike index = [FSA …


Colorado River Cutthroat Trout Habitat Resistance And Resilience To Climate Change, Kate H. Olsen May 2013

Colorado River Cutthroat Trout Habitat Resistance And Resilience To Climate Change, Kate H. Olsen

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Government agencies and private organizations spend large amounts of public money attempting to return ecosystems to a more natural state, which have often been harmed or even destroyed as a result of modern development. Colorado River cutthroat trout, Oncorhyncus clarki pleuriticus, are a subspecies of cutthroat trout. Cutthroat trout live in the Rocky Mountains of the western United States. The population of this particular subspecies has been severely reduced by human actions, and currently only 12% of its historic populations still exist. To improve the condition of cutthroat trout, fisheries professionals and biologists are working to restore natural populations. …


Comparison Of Topographic Surveying Techniques In Streams, Sara G. Bangen May 2013

Comparison Of Topographic Surveying Techniques In Streams, Sara G. Bangen

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The Bonneville Power Administration (BPA) Fish and Wildlife Program (FWP) mitigates impacts, including mortality, from hydroelectric dams in the Columbia River Basin for ESA-listed salmon and steelhead populations and other species of special concern. Given the extensive economic resources invested in mitigation and the incredible diversity of in-stream habitat across the Columbia River basin, questions have arisen about which sampling strategies are most tractable across the entire Columbia River Watershed, but also produce datasets that allow researchers to answer meaningful questions about salmonid populations and trends in habitat. In response to these issues, the NOAA Integrated Status and Effectiveness Monitoring …


Study Of Genes Relating To Degradation Of Aromatic Compounds And Carbon Metabolism In Mycobacterium Sp. Strain Kms, Chun Zhang May 2013

Study Of Genes Relating To Degradation Of Aromatic Compounds And Carbon Metabolism In Mycobacterium Sp. Strain Kms, Chun Zhang

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Polycyclic aromatic hydrocarbons are produced from incomplete combustion of organic materials by human or natural activities. These polycyclic aromatic hydrocarbons are classified as pollutants because of their toxic, mutagenic, and carcinogenic characteristics. Mycobacterium sp. strain KMS, isolated from a contaminated soil, grows on the model polycyclic aromatic hydrocarbon, pyrene, with its degradation to water and carbon dioxide. This study locates genes on the chromosome and plasmids of isolate KMS relating to pyrene degradation, elucidates the influence of other carbon sources available in the habitats of isolate KMS on degradation of pyrene, and deduces possible metabolic pathways used by isolate …


Cougar Predation Behavior In North-Central Utah, Dustin L. Mitchell May 2013

Cougar Predation Behavior In North-Central Utah, Dustin L. Mitchell

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Today’s ability to apply global positioning systems (GPS) collars to wild animals and track their movements, without inadvertently disrupting their daily routine, is a major benefit to wildlife research. Cougars are carnivorous predators that have been identified as being one of several possible causes for recent mule deer population declines throughout the Western United States. Past cougar predation studies have relied on snow tracking, radio-collar tracking, and modeling techniques to estimate cougar prey use and predation rates. These methods rely heavily on weather conditions, logistical availabilities, and broad assumptions, which have led to a wide range of predation rate estimates. …


Mesobiliverdin Ixα Enhances Rat Pancreatic Islet Yield And Function, Taihei Ito, Dong Chen, Cheng-Wei Tom Chang, Takashi Kenmochi, Tomonori Saito, Satoshi Suzuki, Jon Y. Takemoto Apr 2013

Mesobiliverdin Ixα Enhances Rat Pancreatic Islet Yield And Function, Taihei Ito, Dong Chen, Cheng-Wei Tom Chang, Takashi Kenmochi, Tomonori Saito, Satoshi Suzuki, Jon Y. Takemoto

Chemistry and Biochemistry Faculty Publications

The aims of this study were to produce mesobiliverdin IXα, an analog of anti-inflammatory biliverdin IXα, and to test its ability to enhance rat pancreatic islet yield for allograft transplantation into diabetic recipients. Mesobiliverdin IXα was synthesized from phycocyanobilin derived from cyanobacteria, and its identity and purity were analyzed by chromatographic and spectroscopic methods. Mesobiliverdin IXα was a substrate for human NADPH biliverdin reductase. Excised Lewis rat pancreata infused with mesobiliverdin IXα and biliverdin IXα-HCl (1–100 μM) yielded islet equivalents as high as 86.7 and 36.5%, respectively, above those from non-treated controls, and the islets showed a high degree of …


Measuring The Eco-Hydrological Performance Of The Lower Bear River Basin Through Experiential Learning – The Bear River Fellows Program, Liisa Piiparinen, Russell Babb, Sarah Stander, Ayman Alafifi, David E. Rosenberg Apr 2013

Measuring The Eco-Hydrological Performance Of The Lower Bear River Basin Through Experiential Learning – The Bear River Fellows Program, Liisa Piiparinen, Russell Babb, Sarah Stander, Ayman Alafifi, David E. Rosenberg

Spring Runoff Conference

Measuring and evaluating the performance of river systems necessarily requires understanding the variety of environmental and ecological variables driving the decision-making process in managing river basins. Such variables are best understood with field measurements, data analysis and computational modeling. The Department of Civil and Environmental Engineering at Utah State University (USU), through a National Science Foundation project, has partnered with the Outdoor Recreation, and Parks and Recreation programs at USU to offer the Bear River Fellows Program - a new, unique river-based experiential learning opportunity for 5 freshmen Fellows to receive first-hand experience in collecting, synthesizing and analyzing environmental and …


The Magnitude And Mechanism Of Charge Enhancement Of Ch∙∙O H-Bonds, U. Adhikari, Steve Scheiner Jan 2013

The Magnitude And Mechanism Of Charge Enhancement Of Ch∙∙O H-Bonds, U. Adhikari, Steve Scheiner

Chemistry and Biochemistry Faculty Publications

Quantum calculations find that neutral methylamines and thioethers form complexes, with N-methylacetamide (NMA) as proton acceptor, with binding energies of 2–5 kcal/mol. This interaction is magnified by a factor of 4–9, bringing the binding energy up to as much as 20 kcal/mol, when a CH3+ group is added to the proton donor. Complexes prefer trifurcated arrangements, wherein three separate methyl groups donate a proton to the O acceptor. Binding energies lessen when the systems are immersed in solvents of increasing polarity, but the ionic complexes retain their favored status even in water. The binding energy is reduced when the methyl …


Characterization Of A Novel Fusion Protein Of Ipab And Ipad Of Shigella And Its Potential As A Pan-Shigella Vaccine, F. J. Martinez-Becerra, X. Chen, Nicholas E. Dickenson, S. P. Choudhari, K. Harrison, J. D. Clements, W. D. Picking, L. L. Van De Verg, R. I. Walker, W. L. Picking Jan 2013

Characterization Of A Novel Fusion Protein Of Ipab And Ipad Of Shigella And Its Potential As A Pan-Shigella Vaccine, F. J. Martinez-Becerra, X. Chen, Nicholas E. Dickenson, S. P. Choudhari, K. Harrison, J. D. Clements, W. D. Picking, L. L. Van De Verg, R. I. Walker, W. L. Picking

Chemistry and Biochemistry Faculty Publications

Shigellosis is an important disease in the developing world, where about 90 million people become infected with Shigella spp. each year. We previously demonstrated that the type three secretion apparatus (T3SA) proteins IpaB and IpaD are protective antigens in the mouse lethal pulmonary model. In order to simplify vaccine formulation and process development, we have evaluated a vaccine design that incorporates both of these previously tested Shigella antigens into a single polypeptide chain. To determine if this fusion protein (DB fusion) retains the antigenic and protective capacities of IpaB and IpaD, we immunized mice with the DB fusion and compared …


Winter Habitat Use By Juvenile Greater Sage-Grouse On Parker Mountain, Utah: Implications For Sagebrush Management, Danny Caudill, Terry A. Messmer, Brent Bibles, Michael R. Guttery Jan 2013

Winter Habitat Use By Juvenile Greater Sage-Grouse On Parker Mountain, Utah: Implications For Sagebrush Management, Danny Caudill, Terry A. Messmer, Brent Bibles, Michael R. Guttery

Human–Wildlife Interactions

Greater sage-grouse (Centrocercus urophasianus; hereafter, sage-grouse) are entirely dependent on sagebrush (Artemisia spp.) for food and cover during winter. Loss or fragmentation of important wintering areas could have a disproportionate affect on population size. We radio-marked and monitored 91 juvenile sage-grouse in south-central Utah from 2008 to 2010. Thirty-four individuals survived to winter (January to March) and were used to evaluate winter habitat use. Resource use was calculated using kernel density estimation of radio-marked individuals and compared to available habitat using a G-test. We found that juvenile sage-grouse used winter habitats characterized by 0 to 5% slopes …


Vitals Rates And Seasonal Movements Of Two Isolated Greater Sage-Grouse Populations In Utah's West Desert, Jason D. Robinson, Terry A. Messmer Jan 2013

Vitals Rates And Seasonal Movements Of Two Isolated Greater Sage-Grouse Populations In Utah's West Desert, Jason D. Robinson, Terry A. Messmer

Human–Wildlife Interactions

Declines in greater sage-grouse (Centrocercus urophasianus; hereafter, sage-grouse) populations in Utah over the last century parallel range-wide trends. However, little is known about the ecology of sage-grouse populations that inhabit Utah’s naturally fragmented habitats. Utah’s West Desert sage-grouse populations occupy sagebrush (Artemisia spp.) habitats that are geographically separated by the Great Salt Lake, and largely confined to the Sheeprock and Deep Creek watersheds. From 2005 to 2006, we monitored sage-grouse that were radio-collared in each watershed to determine the factors affecting the vital rates in these isolated populations. Livestock grazing by domestic cattle was the dominate land use, …


Livestock Predation By Common Leopard In Binsar Wildlife Sanctuary, India: Human-Wildlife Conflicts And Conservation Issues, Chandra Prakash Kala, Kishor Kumar Kothari Jan 2013

Livestock Predation By Common Leopard In Binsar Wildlife Sanctuary, India: Human-Wildlife Conflicts And Conservation Issues, Chandra Prakash Kala, Kishor Kumar Kothari

Human–Wildlife Interactions

We investigate livestock predation by the common leopard (Panthera pardus) and emerging conflicts between this species, local people, and wildlife authorities at the Binsar Wildlife Sanctuary in the Himalayan region of India. We scrutinized secondary data that were collected by wildlife authorities; we also conducted informal interviews of villagers living within sanctuary, and wildlife staff to understand various human–leopard conflicts. Leopard density was approximately 0.33/km2 in the sanctuary. Leopards killed 1,763 domestic animals, about 90% of which were cattle, during a 14-year period. Within the sanctuary, leopards killed 1 person and injured 9 others. This high depredation rate …


Response To Perryman Comment On Siemer Et Al. (2013), William F. Siemer, Daniel J. Decker, Sandra A. Jonker Jan 2013

Response To Perryman Comment On Siemer Et Al. (2013), William F. Siemer, Daniel J. Decker, Sandra A. Jonker

Human–Wildlife Interactions

No abstract provided.