Physical Sciences and Mathematics Commons^™

Trip: A Method For Novel Transcript Reconstruction From Paired-End Rna-Seq Reads, Serghei Mangul, Adrian Caciula, Dumitru Brinza, Ion I. Măndoiu, Alexander Zelikovskiy

Computer Science Faculty Publications

Preliminary experimental results on synthetic datasets generated with various sequencing parameters and distribution assumptions show that TRIP has increased transcriptome reconstruction accuracy compared to previous methods that ignore fragment length distribution information.