Physical Sciences and Mathematics Commons^™

A Semantic Problem Solving Environment For Integrative Parasite Research: Identification Of Intervention Targets For Trypanosoma Cruzi, Priti Parikh, Todd Minning, Vinh Nguyen, Sarasi Lalithsena, Amir H. Asiaee, Satya S. Sahoo, Prashant Doshi, Rick L. Tarleton, Amit P. Sheth

Kno.e.sis Publications

Background: Research on the biology of parasites requires a sophisticated and integrated computational platform to query and analyze large volumes of data, representing both unpublished (internal) and public (external) data sources. Effective analysis of an integrated data resource using knowledge discovery tools would significantly aid biologists in conducting their research, for example, through identifying various intervention targets in parasites, and in deciding the future direction of ongoing as well as planned projects. A key challenge in achieving this objective is the heterogeneity between the internal lab data, usually stored as flat files, Excel spreadsheets or custom-built databases, and the external …