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Physical Sciences and Mathematics Commons™
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Full-Text Articles in Physical Sciences and Mathematics
Using Computer Algorithms To Elucidate Zebra Finch Reproductive Behaviour, Tanya T. Shoot, Sophie C. Edwards, Robert J. Martin, Susan D. Healy, David F. Sherry, Mark J. Daley
Using Computer Algorithms To Elucidate Zebra Finch Reproductive Behaviour, Tanya T. Shoot, Sophie C. Edwards, Robert J. Martin, Susan D. Healy, David F. Sherry, Mark J. Daley
Western Research Forum
Birds that experience variation in climatic conditions must maintain a stable nest temperature during incubation for successful hatching of offspring. Varying nest structure and incubation behaviour may be the methods birds use to regulate nest temperature. We used a modeling approach to investigate how birds adjust incubation behaviour to ambient temperature.
Hidden Markov Models (HMM) have been used previously to predict the spatial distribution of animals based on the models’ ability to classify movement behaviour. We used a HMM to predict zebra finch (Taeniopygia guttata) incubation behaviour and nest structure from a nest temperature data set. The full …
Tinnitus And Dysfunctional Interactions Between Distributed Resting State Networks, Sivayini Kandeepan
Tinnitus And Dysfunctional Interactions Between Distributed Resting State Networks, Sivayini Kandeepan
Western Research Forum
It is known that peripheral lesions in the cochlea or the auditory nerve produce dysfunctional input to central auditory structures and induce changes in the auditory system causing tinnitus. Recently, it has been proposed that the unified percept of tinnitus could be considered as an emergent property of multiple overlapping dynamic brain networks, each encoding a specific tinnitus characteristic.
The aim of our study was to investigate the neuronal activation patterns associated with specific clinical tinnitus characteristics using fMRI. We hypothesize that tinnitus clinical characteristics could be associated with specific resting-state activity and connectivity patterns and that this could be …
A Chimeric Nucleobase - Phenylazo Derivative As An Intrinsic Nucleobase Quencher, Gyeongsu Park, Timothy Martin-Chan, Amer El Samm, Robert H.E. Hudson
A Chimeric Nucleobase - Phenylazo Derivative As An Intrinsic Nucleobase Quencher, Gyeongsu Park, Timothy Martin-Chan, Amer El Samm, Robert H.E. Hudson
Western Research Forum
Molecular beacons are important bioanalytical probes which are most often
constructed from a single-stranded oligonucleotide which has been labeled at
opposite termini with a fluorophore and a quencher. When the fluorophore and
quencher are in close proximity, no fluorescence is observed due to FRET
(Fluorescence Resonance Energy Transfer). DABCYL (4-dimethylaminoazobenzene-
4'-carboxylic acid) has been used as a quencher in the molecular beacon to absorbs
excitation energy from a fluorophore and to dissipate the energy as heat. However,
DABCYL is unable to form a base-pair and is conventionally placed as an overhanging
residue. This produces a derivative wherein the chromophore has …