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- Agricultural Hydrology (1)
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- Amyloid-beta plaque development (1)
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Articles 1 - 30 of 35
Full-Text Articles in Physical Sciences and Mathematics
Stochastic Analysis Of A Mammalian Circadian Clock Model: Small Protein Number Effects, David W. Morgens, Blerta Shtylla
Stochastic Analysis Of A Mammalian Circadian Clock Model: Small Protein Number Effects, David W. Morgens, Blerta Shtylla
Spora: A Journal of Biomathematics
The circadian clock, responsible for coordinating organism function with daily and seasonal changes in the day-night cycle, is controlled by a complex protein network that constitutes a robust biochemical oscillator. Deterministic ordinary differential equation models have been used extensively to model the behavior of these central clocks. However, due to the small number of proteins involved in the circadian oscillations, mathematical models that track stochastic variations in the numbers of clock proteins may reveal more complex and biologically relevant behaviors. In this paper, we compare the response of a robust yet detailed deterministic model for the mammalian circadian clock with …
Examining The Electrical Excitation, Calcium Signaling, And Mechanical Contraction Cycle In A Heart Cell, Kristen Deetz, Nygel Foster, Darius Leftwich, Chad Meyer, Shalin Patel, Carlos Barajas, Matthias K. Gobbert, Zana Coulibaly
Examining The Electrical Excitation, Calcium Signaling, And Mechanical Contraction Cycle In A Heart Cell, Kristen Deetz, Nygel Foster, Darius Leftwich, Chad Meyer, Shalin Patel, Carlos Barajas, Matthias K. Gobbert, Zana Coulibaly
Spora: A Journal of Biomathematics
As the leading cause of death in the United States, heart disease has become a principal concern in modern society. Cardiac arrhythmias can be caused by a dysregulation of calcium dynamics in cardiomyocytes. Calcium dysregulation, however, is not yet fully understood and is not easily predicted; this provides motivation for the subsequent research. Excitation-contraction coupling (ECC) is the process through which cardiomyocytes undergo contraction from an action potential. Calcium induced calcium release (CICR) is the mechanism through which electrical excitation is coupled with mechanical contraction through calcium signaling. The study of the interplay between electrical excitation, calcium signaling, and mechanical …
Age-Structured And Vaccination Models Of Devil Facial Tumor Disease, Christopher D. Bruno, Timothy Comar, Megan O. Powell, Adjo Tameklo
Age-Structured And Vaccination Models Of Devil Facial Tumor Disease, Christopher D. Bruno, Timothy Comar, Megan O. Powell, Adjo Tameklo
Spora: A Journal of Biomathematics
Tasmanian devil populations have been devastated by devil facial tumor disease (DFTD) since its first appearance in 1996. The average lifespan of a devil has decreased from six years to three years. We present an age-structured model to represent how the disease has affected the age and breeding structures of the population. We show that with the recent increase in the breeding of juvenile devils, the overall devil population will increase but not nearly to pre-DFTD levels. The basic reproductive number may be increased with the influx of young breeding devils. In addition, our model shows that the release of …
Modeling Aggregation Of Proliferating Microglia In Response To Amyloid-Beta In Dementia, Adrienne C. Kinney, Ellen R. Swanson
Modeling Aggregation Of Proliferating Microglia In Response To Amyloid-Beta In Dementia, Adrienne C. Kinney, Ellen R. Swanson
Spora: A Journal of Biomathematics
Amyloid-beta plaques are prominent biological markers in dementia brains. In response to plaque formation, the brain's immune cells, microglia, become reactive. Microglia are measurable cells that surround amyloid-beta plaques, indicating their location. A system of partial differential equations describes the concentration of microglia in dementia brains by incorporating chemotactic signaling. However, this system fails to incorporate increasing numbers of reactive microglia cells in response to amyloid-beta aggregation. A system of ordinary differential equations describing the number of significant cells and proteins in the brain suggests the amount of reactive microglia increases significantly during the progression of dementia. We couple these …
The Biochemical Assessment Of Two Secreted Acid Phosphatases From Leishmania Tarentolae, Their Response To Electric Fields, Glycosidase Incubation, And / Or Vanadium, Benjamin M. Dorsey
The Biochemical Assessment Of Two Secreted Acid Phosphatases From Leishmania Tarentolae, Their Response To Electric Fields, Glycosidase Incubation, And / Or Vanadium, Benjamin M. Dorsey
Theses and Dissertations
Leishmaniasis, as defined by the Center for Disease Control and Prevention, is a neglected tropical disease with 1.6 million new cases reported each year. However, there is yet to be safe, effective, and affordable treatments provided to those affected by this disease1. Still underappreciated as a potential pharmaceutical targets, especially for cutaneous leishmaniasis infections, are the two isozymes of secreted acid phosphatase (SAP); secreted acid phosphatase 1 (SAP1) and secreted acid phosphatase 2 (SAP2). These enzymes are involved in the survival of the parasite in the sand fly vector, and the prevention of host macrophages from forming parasitophorous vacuole and …
Kinetic Characterization Of Listeria Monocytogenes 2-C- Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase ( Cms ) Enzymes Using High Performance Liquid Chromatography ( Hplc ), Mark Oblazny
Theses and Dissertations
Infectious diseases, with increasing prevalence of antibiotic resistant bacteria, coupled with the declining rate in discovery of antimicrobial agents, impose one of the most significant threats to human health. Here we identify 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (CMS) as a valid target for antibiotic development which is an enzyme in pathogenic organisms that leads to the biosynthesis of isoprene precursor molecules. Isoprene molecules are one of nature’s most common building blocks that are vital to many biological metabolic processes and are synthesized via the mevalonic acid dependent (MVA), or methylerythritol phosphate (MEP) pathway. Vertebrates utilize the MVA pathway, while many pathogenic bacteria …
Heads And Tails, Julie Simons
Heads And Tails, Julie Simons
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
A Cellular Automaton Modeling Approach To Chestnut Blight Canker Development, Samuel Iselin
A Cellular Automaton Modeling Approach To Chestnut Blight Canker Development, Samuel Iselin
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Turning Monitoring Data Into Simple Population Growth Models: Getting Your Ducks In A Row, Holly Gaff
Turning Monitoring Data Into Simple Population Growth Models: Getting Your Ducks In A Row, Holly Gaff
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Model Selection And Permanence In A Stochastic Integrated Pest Management Model, Timothy Comar, Olcay Akman, Daniel Hrozencik
Model Selection And Permanence In A Stochastic Integrated Pest Management Model, Timothy Comar, Olcay Akman, Daniel Hrozencik
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Agent-Based Model For Integrated Pest Management With Periodic Control Strategies, Timothy Comar, Elizabeth Rodriguez
Agent-Based Model For Integrated Pest Management With Periodic Control Strategies, Timothy Comar, Elizabeth Rodriguez
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Yeast Cell Cycle And Metabolism Can Be Coupled In Nontrivial Ways., Todd Young
Yeast Cell Cycle And Metabolism Can Be Coupled In Nontrivial Ways., Todd Young
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Stochastic And Deterministic Multigroup Epidemiology, Jordan Hasler, Chris Chang, Ananya Yammanuru, Lewis Oh, Esther Matthew, Mounisha Kovour
Stochastic And Deterministic Multigroup Epidemiology, Jordan Hasler, Chris Chang, Ananya Yammanuru, Lewis Oh, Esther Matthew, Mounisha Kovour
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
The Behavior Response Of Antlion Larvae To Alternating Magnetic Fields, Lindsey Wagner, Caleb L. Adams
The Behavior Response Of Antlion Larvae To Alternating Magnetic Fields, Lindsey Wagner, Caleb L. Adams
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
A Critical Firing Rate In Synchronous Transitions Of Coupled Neurons, Annabelle Shaffer, Epaminondas Rosa, Rosangela Follmann
A Critical Firing Rate In Synchronous Transitions Of Coupled Neurons, Annabelle Shaffer, Epaminondas Rosa, Rosangela Follmann
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
The Kinetics Of Type I Interferons During Influenza A Virus Infection, Margaret A. Myers
The Kinetics Of Type I Interferons During Influenza A Virus Infection, Margaret A. Myers
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Handicap Principle Implies Emergence Of Dimorphic Ornaments, Sara Clifton, Daniel M. Abrams, Rosemary I. Braun
Handicap Principle Implies Emergence Of Dimorphic Ornaments, Sara Clifton, Daniel M. Abrams, Rosemary I. Braun
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Should I Get A Flu Shot? How Well Did This Go Last Year?, Winfried Just, David Gerberry, Ying Xin
Should I Get A Flu Shot? How Well Did This Go Last Year?, Winfried Just, David Gerberry, Ying Xin
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling Cdc42 Oscillation In Fission Yeast, Bin Xu
Modeling Cdc42 Oscillation In Fission Yeast, Bin Xu
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
One Tick, Two Tick, Two Pathogens, Oh No! Am I Sick?, Caleb L. Adams
One Tick, Two Tick, Two Pathogens, Oh No! Am I Sick?, Caleb L. Adams
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling Microtubule-Based Transport In The Frog Egg Cell, Maria-Veronica Ciocanel
Modeling Microtubule-Based Transport In The Frog Egg Cell, Maria-Veronica Ciocanel
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Food Web Control And Synchronization Using A Robust Feedback, Hector Puebla, Mariana Rodriguez-Jara, Cesar S. Lopez-Monsalvo, Eliseo Hernandez-Martinez, Alejandra Velasco-Perez
Food Web Control And Synchronization Using A Robust Feedback, Hector Puebla, Mariana Rodriguez-Jara, Cesar S. Lopez-Monsalvo, Eliseo Hernandez-Martinez, Alejandra Velasco-Perez
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
A Model Of Dengue Transmission With Wolbachia-Free And Wolbachia-Infected Mosquitoes, Iftikhar Ahmed
A Model Of Dengue Transmission With Wolbachia-Free And Wolbachia-Infected Mosquitoes, Iftikhar Ahmed
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
The Effects Of Evolution On Food Web Diversity And Abundance, Rosalyn Rael
The Effects Of Evolution On Food Web Diversity And Abundance, Rosalyn Rael
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling The Influence Of El Niño On Parasite Transmission In Sand Crab Populations And Seabird Abundance Along The California Coast, James Peirce, Olcay Akman, Abou Seck
Modeling The Influence Of El Niño On Parasite Transmission In Sand Crab Populations And Seabird Abundance Along The California Coast, James Peirce, Olcay Akman, Abou Seck
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
The Role Of Intermittent Preventive Treatment For Malaria In Saving Lives And Promoting Drug Resistance, Carrie Manore
The Role Of Intermittent Preventive Treatment For Malaria In Saving Lives And Promoting Drug Resistance, Carrie Manore
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Cnemidophorus Sexlineatus And The Impacts The Environment Has On Its Population At The Braidwood Dunes, Jeremiah Soto
Cnemidophorus Sexlineatus And The Impacts The Environment Has On Its Population At The Braidwood Dunes, Jeremiah Soto
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Land Cover Change Shows Little Effect On Migration Patterns Of Wood Storks And Great Egrets, Johanna Smith
Land Cover Change Shows Little Effect On Migration Patterns Of Wood Storks And Great Egrets, Johanna Smith
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling Habitat Suitability Of Invasive Carps In The Upper Missisisippi River System, Charlotte Alexander, Robert F. Allen, Kevin J. Aagard
Modeling Habitat Suitability Of Invasive Carps In The Upper Missisisippi River System, Charlotte Alexander, Robert F. Allen, Kevin J. Aagard
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Development Of Epithelial Tissues: How Are Cleavage Planes Chosen?, Ying Xin
Development Of Epithelial Tissues: How Are Cleavage Planes Chosen?, Ying Xin
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.