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Life Sciences

Claremont Colleges

Pomona Faculty Publications and Research

Cell behavior

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Full-Text Articles in Physical Sciences and Mathematics

Do Longer Delays Matter? The Effect Of Prolonging Delay In Ctl Activation, Angela Gallegos, Ami E. Radunskaya Jan 2011

Do Longer Delays Matter? The Effect Of Prolonging Delay In Ctl Activation, Angela Gallegos, Ami E. Radunskaya

Pomona Faculty Publications and Research

The activation of a specific immune response takes place in the lymphoid organs such as the spleen. We present here a simplified model of the proliferation of specific immune cells in the form of a single delay equation. We show that the system can undergo switches in stability as the delay is increased, and we interpret these results in the context of sustaining an effective immune response to a dendritic cell vaccine.