Physical Sciences and Mathematics Commons^™

Machine Learning Analysis Of Single Nucleotide Polymorphism (Snp) Data To Predict Bone Mineral Density In African American Women, Erick Githua Wakayu

UNLV Theses, Dissertations, Professional Papers, and Capstones

Osteoporosis is a debilitating disease in which an individual’s bones weaken, making bones fragile and more susceptible to fracture. While commonly found amongst postmenopausal Caucasian and Asian women based on previous studies, those of African descent (African American/Black) have largely been ignored when it comes to osteoporotic studies, especially when it comes to Genome Wide Association Studies (GWAS). From GWA studies, we gain access to single nucleotide poly-morphisms (SNPs) that may contribute to certain illnesses, such as osteoporosis. With low Bone Mineral Density (BMD) being one of the primary markers of potential osteoporosis, it is prudent that proper research is …

Characterizing The Behavior Of Mutated Proteins With Emcap: The Energy Minimization Curve Analysis Pipeline, Matthew Lee, Bodi Van Roy, Filip Jagodzinski

WWU Honors College Senior Projects

Studies of protein mutants in wet laboratory experiments are expensive and time consuming. Computational experiments that simulate the motions of protein with amino acid substitutions can complement wet lab experiments for studying the effects of mutations. In this work we present a computational pipeline that performs exhaustive single-point amino acid substitutions in silico. We perform energy minimization as part of molecular dynamics (MD) of our generated mutant proteins, and the wild type, and log the energy potentials for each step of the simulations. We motivate several metrics that rely on the energy minimization curves of the wild type and mutant, …

Pollinator Power: Supporting Bees Through Ecoregion Specific Planting Guides, Maya Thomas

Scripps Senior Theses

The pollination of flowering crops by bees is an invaluable ecosystem service that supports biodiversity and much of the global agricultural system. Pollinators move pollen between the male structures of a plant to the female structures of a plant of the same species. This fertilizes the female plant, which then produces the next generation. This process also provides the pollinator with the nectar or pollen it needs to survive. While some plants transfer pollen through different means, the majority of plants need help from pollinators to reproduce. Depending on the means of pollination, pollination can be classified as abiotic or …

A Dynamic Behavioral Biometric Approach To Authenticate Users Employing Their Fingers To Interact With Touchscreen Devices, Arturo Ponce

CCE Theses and Dissertations

The use of mobile devices has extended to all areas of human life and has changed the way people work and socialize. Mobile devices are susceptible to getting lost, stolen, or compromised. Several approaches have been adopted to protect the information stored on these devices. One of these approaches is user authentication. The two most popular methods of user authentication are knowledge based and token based methods but they present different kinds of problems.

Biometric authentication methods have emerged in recent years as a way to deal with these problems. They use an individual’s unique characteristics for identification and have …

Design, Programming, And User-Experience, Kaila G. Manca

Honors Scholar Theses

This thesis is a culmination of my individualized major in Human-Computer Interaction. As such, it showcases my knowledge of design, computer engineering, user-experience research, and puts into practice my background in psychology, com- munications, and neuroscience.

I provided full-service design and development for a web application to be used by the Digital Media and Design Department and their students.This process involved several iterations of user-experience research, testing, concepting, branding and strategy, ideation, and design. It lead to two products.

The first product is full-scale development and optimization of the web appli- cation.The web application adheres to best practices. It was …

07. Criminal Justice, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

04. Botany, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

06. Computer Science, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

03. Biology, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

08. Engineering, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

10. Forensic Science, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

11. Genetics, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

14. Optometry, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

16. Physics, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

17. Psychology, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

13. Mathematics, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

18. Statistics, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

02. Animal Science, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

05. Chemistry, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

09. Environmental Science, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

12. Kinesiology, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

15. Pharmacy, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

19. Zoology, Northeastern State University

Oklahoma Research Day Abstracts

No abstract provided.

Learning Emotions: A Software Engine For Simulating Realistic Emotion In Artificial Agents, Douglas Code

Senior Independent Study Theses

This paper outlines a software framework for the simulation of dynamic emotions in simulated agents. This framework acts as a domain-independent, black-box solution for giving actors in games or simulations realistic emotional reactions to events. The emotion management engine provided by the framework uses a modified Fuzzy Logic Adaptive Model of Emotions (FLAME) model, which lets it manage both appraisal of events in relation to an individual’s emotional state, and learning mechanisms through which an individual’s emotional responses to a particular event or object can change over time. In addition to the FLAME model, the engine draws on the design …

Evaluation Of The Signature Molecular Descriptor With Blosum62 And An All-Atom Description For Use In Sequence Alignment Of Proteins, Lindsay M. Aichinger

Williams Honors College, Honors Research Projects

This Honors Project focused on a few aspects of this topic. The second is comparing the molecular signature kernels to three of the BLOSUM matrices (30, 62, and 90) to test the accuracy of the mathematical model. The kernel matrix was manipulated in order to improve the relationship by focusing on side groups and also by changing how the structure was represented in the matrix by increasing the initial height distance from the central atom (Height 1 and Height 2 included).

There were multiple design constraints for this project. The first was the comparison with the BLOSUM matrices (30, 62, …

Abduction In Annotated Logic Programming, Krishnaprasad Thirunarayan

Kno.e.sis Publications

The author investigates techniques to make the logic programming paradigm more expressive for knowledge representation, while simultaneously retaining the computational advantages of efficiency and simplicity. He extends the annotated language of K. Thirunarayan and K. Kifer (1989) in various directions to obtain an enriched representation language. In particular, rule bodies are permitted to be a conjunction of literals, and the rules to be recursive. A class of annotated logic programs called the stratified programs is identified which can be given a unique supported minimal Herbrand model as their meaning. Abductive reasoning is integrated into this annotated logic framework. The notion …

On The Relationship Between Parsimonious Covering And Boolean Minimization, Venu Dasigi, Krishnaprasad Thirunarayan

Kno.e.sis Publications

Minimization of Boolean switching functions is a basic problem in the design of logic circuits. The designer first comes up with a switching function expressed in terms of several binary input variables that satisfies the desired functionality, and then attempts to minimize the function as a sum of products or product of sums. It turns out that a sum of products form of a switching function that has no redundancy is a union of prime implicants of the function.

In this paper we would like to explicate some of the relationships of the boolean minimization problem to a formalization of …