Physical Sciences and Mathematics Commons^™

Adjusting Population Estimates For Genotyping Error In Non-Invasive Dna-Based Mark-Recapture Experiments, Shannon M. Knapp, Bruce A. Craig

Conference on Applied Statistics in Agriculture

DNA from non-invasive sources is increasingly being used as molecular tags for markrecapture population estimation. These sources, however, provide small quantities of often contaminated DNA, which can lead to genotyping errors that will bias the population estimate. We describe a novel approach, called Genotyping Uncertainty Added Variance Adjustment (GUAVA), to address this problem. GUAVA incorporates an explicit model of genotyping error to generate a distribution of complete-information capture histories that is used to estimate the population size. This approach both reduces the genotyping-error bias and incorporates the additional uncertainty due to genotyping error into the variance of the estimate. We …