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Selected Works

Borbala Mazzag

Articles 1 - 8 of 8

Full-Text Articles in Physical Sciences and Mathematics

Using Math In Cell Biology: A Tale Of Two Channel Types, Borbala Mazzag Mar 2007

Using Math In Cell Biology: A Tale Of Two Channel Types, Borbala Mazzag

Borbala Mazzag

No abstract provided.


Computational Modeling Of Calcium Dynamics Near Heterogeneous Release Sites, Borbala Mazzag, Zachary Cooper, Michael Greenwood Dec 2006

Computational Modeling Of Calcium Dynamics Near Heterogeneous Release Sites, Borbala Mazzag, Zachary Cooper, Michael Greenwood

Borbala Mazzag

Background: Calcium is known to play an important role in many physiological
processes, such as egg fertilization and heart muscle functions.
Several recent theoretical studies ([4], [1]) investigated calcium dynamics
near so-called release sites – clusters of calcium-regulated channels on
the intracellular calcium stores. Interest in the synchronized openings of
channels within a release site has increased because these openings are
thought to be the building blocks of global calcium events.
Methods: We conduct computational studies of the effect of heterogeneity
in the make-up of the release site on the resulting calcium dynamics.
We introduce heterogeneity into the model of …


The Localized Dynamics Of A Ca2+Channel (30-Minute Talk), Borbala Mazzag, Christoper Tignanelli, Gregory D. Smith Aug 2006

The Localized Dynamics Of A Ca2+Channel (30-Minute Talk), Borbala Mazzag, Christoper Tignanelli, Gregory D. Smith

Borbala Mazzag

No abstract provided.


Graduate Colloquium, Borbala Mazzag Aug 2005

Graduate Colloquium, Borbala Mazzag

Borbala Mazzag

No abstract provided.


Using Math In Cell Biology How Do Calcium Channels Work?, Borbala Mazzag Feb 2004

Using Math In Cell Biology How Do Calcium Channels Work?, Borbala Mazzag

Borbala Mazzag

No abstract provided.


A Model For Shear Stress Sensing And Transmission In Vascular Endothelial Cells, Borbala Mazzag, John S. Tamaresis, Abdul Barakat May 2003

A Model For Shear Stress Sensing And Transmission In Vascular Endothelial Cells, Borbala Mazzag, John S. Tamaresis, Abdul Barakat

Borbala Mazzag

 Arterial endothelial cell (EC) responsiveness to flow is essential for normal vascular function and plays a role in the development of atherosclerosis. EC flow responses may involve sensing of the mechanical stimulus at the cell surface with subsequent transmission via cytoskeleton to intracellular transduction sites. We had previously modeled flow-induced deformation of EC-surface flow sensors represented as viscoelastic materials with standard linear solid behavior (Kelvin bodies). In the present article, we extend the analysis to arbitrary networks of viscoelastic structures connected in series and/or parallel. Application of the model to a system of two Kelvin bodies in parallel reveals that …


A Mathematical Model Of Bacterial Aerotaxis, Borbala Mazzag, Alex Mogilner Sep 2002

A Mathematical Model Of Bacterial Aerotaxis, Borbala Mazzag, Alex Mogilner

Borbala Mazzag

No abstract provided.


Mathematical Models In Biology, Borbala Mazzag Dec 2001

Mathematical Models In Biology, Borbala Mazzag

Borbala Mazzag

No abstract provided.