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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

Predicting Coronary Artery Disease With Medical Profile And Gene Polymorphisms Data, Qiongyu Chen, Guoliang Li, Tze-Yun Leong, Chew-Kiat Heng Aug 2007

Predicting Coronary Artery Disease With Medical Profile And Gene Polymorphisms Data, Qiongyu Chen, Guoliang Li, Tze-Yun Leong, Chew-Kiat Heng

Research Collection School Of Computing and Information Systems

Coronary artery disease (CAD) is a main cause of death in the world. Finding cost-effective methods to predict CAD is a major challenge in public health. In this paper, we investigate the combined effects of genetic polymorphisms and non-genetic factors on predicting the risk of CAD by applying well known classification methods, such as Bayesian networks, naïve Bayes, support vector machine, k-nearest neighbor, neural networks and decision trees. Our experiments show that all these classifiers are comparable in terms of accuracy, while Bayesian networks have the additional advantage of being able to provide insights into the relationships among the variables. …


A Time-And-Value Centric Provenance Model And Architecture For Medical Event Streams, Marion Bllount, John Davis, Archan Misra, Daby Sow, Min Wang Jun 2007

A Time-And-Value Centric Provenance Model And Architecture For Medical Event Streams, Marion Bllount, John Davis, Archan Misra, Daby Sow, Min Wang

Research Collection School Of Computing and Information Systems

Provenance becomes a critical requirement for healthcare IT infrastructures, especially when pervasive biomedical sensors act as a source of raw medical streams for large-scale, automated clinical decision support systems. Medical and legal requirements will make it obligatory for such systems to answer queries regarding the underlying data samples from which output alerts are derived, the IDs of the processing components used and the privileges of the individuals and software components accessing the medical data. Unfortunately, existing models of either annotation or process based provenance are designed for transaction-oriented systems and do not satisfy the unique requirements for systems processing high-volume, …