Physical Sciences and Mathematics Commons^™

Antibiotic Resistance Of Helicobacter Pylori Strains In The United Arab Emirates And Its Relation To The Gene Associated To Gastric Cancer “Cag A Gene”, Wafa Ali Rashid Al-Tayyari

Theses

Helicobacter pylori is a flagellated corkscrew, slow growing neutrophilic gram negative ureolytic organism. It has an extraordinary ability to establish infection in human stomach that can last for years or decades. Its eradication remains an important public health challenge especially in light of broadening indications and increasing antimicrobial resistance.

AIM: i) Identification of H. pylori in UAE patients ii) Determination of the prevalence of antibiotic resistance genes (mutation in 23S rRNA gene in clarithromycin, and deletion in RdxA gene in metronidazole) among H. pylori strains isolated from U.A.E patients by using molecular methods, iii) Ascertain whether Cag A- positive H. …