Physical Sciences and Mathematics Commons^™

Multipoint Spectroscopy And Stereoscopic Imaging Of Pharmaceutical Particles, Hicham Rifai

Masters

Particle and granule properties play a key role in the final product quality of pharmaceuticals. Thus the identification and monitoring of key chemical and physical parameters is essential in the production of pharmaceuticals. The existing off-line methods are generally slow and labour intensive. Near infra-red (NIR) multipoint spectroscopy and image analysis are an attractive alternative compared to the traditional methods because they are both nondestructive and non-interfering allowing the analysis in real time of particles physical and chemical properties. This research is a preliminary study performed at laboratory scale and aims at developing chemometric and imaging algorithms for real time …