Physical Sciences and Mathematics Commons^™

Pegylation Of Platinum Bio-Electrodes, Zhilian Yue, Paul J. Molino, Xiao Liu, Gordon G. Wallace

Gordon Wallace

Controlling protein interactions at the implanted electrode interface is becoming an important strategy for the management of foreign body responses that have proven to be detrimental to the long-term performance of neural prosthesis. In this study, PEGylation was conducted on platinum bio-electrodes to render the surface protein-resistant. The PEGylated electrode was investigated using a quartz crystal microbalance-dissipation, electrochemical impedance spectroscopy and cyclic voltammetiy.