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Full-Text Articles in Physical Sciences and Mathematics

Individual-Level Simulation Model For Cost Benefit Analysis In Healthcare, Nagesh Shukla, Vu Lam Cao, Van Hoang Phuong, Marian D. Shanahan, Alison Ritter, Pascal Perez Jan 2016

Individual-Level Simulation Model For Cost Benefit Analysis In Healthcare, Nagesh Shukla, Vu Lam Cao, Van Hoang Phuong, Marian D. Shanahan, Alison Ritter, Pascal Perez

SMART Infrastructure Facility - Papers

Illicit drug use creates significant burden at societal, family and personal levels. Every year substantial resources are allocated for treatment and the consequences of illicit drug use in Australia and around the world. Heroin is one of the major forms of illicit drugs. Several independent heroin treatment strategies or interventions exist and state-of-the art research demonstrates their efficacy and relative costeffectiveness. However, assessing total potential gains and burden from providing all treatment interventions or varying the mix of heroin treatments has never been attempted. This paper proposed an individual-level simulation model (ISM) which addresses net social benefit over a lifetime …


Tensile Testing Of Individual Glassy, Rubbery And Hydrogel Electrospun Polymer Nanofibres To High Strain Using The Atomic Force Microscope, Adrian Gestos, Philip G. Whitten, Geoffrey M. Spinks, Gordon G. Wallace Jan 2013

Tensile Testing Of Individual Glassy, Rubbery And Hydrogel Electrospun Polymer Nanofibres To High Strain Using The Atomic Force Microscope, Adrian Gestos, Philip G. Whitten, Geoffrey M. Spinks, Gordon G. Wallace

Australian Institute for Innovative Materials - Papers

The production and use of polymer nanofibre assemblies prepared by electrospinning is now widespread. It is known that the tensile properties of electrospun polymer fibres can be different to those of bulk polymers. Here, we report a general method for measuring the tensile properties of individual electrospun nanofibres that employs a commercial atomic force microscope. Methods for preparing samples, force calibration and calculation of tensile stress and strain are described along with error estimation. By appropriate choice of AFM cantilever, it is shown that the tensile stress-strain curves can be measured for glassy, rubbery and gel polymer nanofibres. Testing can …


Actuating Individual Electrospun Hydrogel Nanofibres, Adrian Gestos, Philip G. Whitten, Gordon G. Wallace, Geoffrey Maxwell Spinks Jan 2012

Actuating Individual Electrospun Hydrogel Nanofibres, Adrian Gestos, Philip G. Whitten, Gordon G. Wallace, Geoffrey Maxwell Spinks

Australian Institute for Innovative Materials - Papers

The actuation of a single hydrogel nanofibre is measured for the first time by AFM. The actuation stress generated was comparable to that produced by skeletal muscle and the actuation rate was significantly increased by the nanoscale dimensions of the fibre.


Direct Imaging Of Individual Intrinsic Hydration Layers On Lipid Bilayers With Angstrom Resolution, Takeshi Fukuma, Michael J. Higgins, Suzanne P. Jarvis Jan 2007

Direct Imaging Of Individual Intrinsic Hydration Layers On Lipid Bilayers With Angstrom Resolution, Takeshi Fukuma, Michael J. Higgins, Suzanne P. Jarvis

Australian Institute for Innovative Materials - Papers

The interactions between water and biological molecules have the potential to influence the structure, dynamics, and function of biological systems, hence the importance of revealing the nature of these interactions in relation to the local biochemical environment. We have investigated the structuring of water at the interface of supported dipalmitoylphosphatidylcholine bilayers in the gel phase in phosphate buffer solution using frequency modulation atomic force microscopy (FM-AFM). We present experimental results supporting the existence of intrinsic (i.e., surface-induced) hydration layers adjacent to the bilayer. The force versus distance curves measured between the bilayer and the AFM tip show oscillatory force profiles …


Nanomanipulation Of Individual Carbon Nanotubes, Rishi Gupta, Taylor M. Cavanah, Marc In Het Panhuis Jan 2004

Nanomanipulation Of Individual Carbon Nanotubes, Rishi Gupta, Taylor M. Cavanah, Marc In Het Panhuis

Australian Institute for Innovative Materials - Papers

Extended abstract of a paper presented at Microscopy and Microanalysis 2004 in Savannah, Georgia, USA, August 1-5, 2004.