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Computational Solutions To Exosomal Microrna Biomarker Detection In Pancreatic Cancer, Thuy T. An
Computational Solutions To Exosomal Microrna Biomarker Detection In Pancreatic Cancer, Thuy T. An
Department of Computer Science and Engineering: Dissertations, Theses, and Student Research
Pancreatic cancer is the fourth leading cause of cancer death in the United States and the 5-year survival rate is only 5% to 10%. There are only a few non-specific symptoms associated with the early-stage cancer, therefore most patients are diagnosed in a late stage. Due to the lack of effective treatments and the fact that the early stage has a 39% 5-year survival rate, the biggest hope to control this disease is early detection. Therefore, discovery of effective and reliable non-invasive biomarkers for early detection of pancreatic cancer has been a major topic. Very recently, exosomal microRNAs have become …