Physical Sciences and Mathematics Commons^™

Rat Brain Pro-Oxidant Effects Of Peripherally Administered 5 Nm Ceria 30 Days After Exposure, Sarita S. Hardas, Rukhsana Sultana, Govind Warrier, Mo Dan, Rebecca L. Florence, Peng Wu, Eric A. Grulke, Michael T. Tseng, Jason M. Unrine, Uschi M. Graham, Robert A. Yokel, D. Allan Butterfield

Chemistry Faculty Publications

The objective of this study was to determine the residual pro-or anti-oxidant effects in rat brain 30 days after systemic administration of a 5 nm citrate-stabilized ceria dispersion. A ∼4% aqueous ceria dispersion was iv-infused (0 or 85 mg/kg) into rats which were terminated 30 days later. Ceria concentration, localization, and chemical speciation in the brain was assessed by inductively coupled plasma mass spectrometry (ICP-MS), light and electron microscopy (EM), and electron energy loss spectroscopy (EELS), respectively. Pro- or anti-oxidant effects were evaluated by measuring levels of protein carbonyls (PC), 3-nitrotyrosine (3NT), and protein-bound-4-hydroxy-2-trans-nonenal (HNE) in the hippocampus, cortex, and …

Concentration Effects And Ion Properties Controlling The Fractionation Of Halides During Aerosol Formation, Marcelo I. Guzman, Richa R. Athalye, Jose M. Rodriguez

Chemistry Faculty Publications

During the aerosolization process at the sea surface, halides are incorporated into aerosol droplets, where they may play an important role in tropospheric ozone chemistry. Although this process may significantly contribute to the formation of reactive gas phase molecular halogens, little is known about the environmental factors that control how halides selectively accumulate at the air-water interface. In this study, the production of sea spray aerosol is simulated using electrospray ionization (ESI) of 100 nM equimolar solutions of NaCl, NaBr, NaI, NaNO(2), NaNO(3), NaClO(4), and NaIO(4). The microdroplets generated are analyzed by mass spectrometry to study the comparative enrichment of …

Multi-Dimensional Modeling Of Charring Ablators, Haoyue Weng, Huaibao Zhang, Ovais U. Khan, Alexandre Martin

Mechanical Engineering Faculty Publications

Re-entry of a spacecraft occurs at the hypersonic regime where the flow field is extremely complex: high temperature gradients occurring in the shock-layer region ionize and dissociate the air. Even if a large portion of heat generated during this process is convected away in the surrounding air, a fraction of it is still transferred to the vehicle. Therefore, it is important to protect the vehicle with a suitable kind of shielding. Of the many techniques available today, use of ablative material is gaining popularity. The basic idea behind an ablating heat shield is that the energy incident on the spacecraft …

Poster Session, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• Western Kentucky Deep Saline Reservoir CO₂ Storage Test: Shallow Groundwater Monitoring Results, E. Glynn Beck and others, Kentucky Geological Survey
• Baseline Soil Properties of a Central Kentucky Riparian Buffer, Amanda Gumbert and others, Dept of Plant and Soil Science, UK
• The Kentucky Water Well Driller’s Certification Program, Scotty E. Robertson and David A. Jackson, Kentucky Division of Water, Frankfort, KY
• Influences of Cladophora Bloom on the Diets of Amblema plicata and Elliptio dilatata in the Upper Green River, Kentucky, Jennifer M. Yates and others, Dept of Biology, Western Kentucky University
• Using Electrical Resistivity to Locate …

Session 2c, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• The Developing Need for the Regulation of Geothermal Closed Loop Borehole Installations, David A. Jackson, Kentucky Division of Water, Frankfort, KY
• Strategies for Effective Management and Mitigation of Nonpoint Source Pollution within Wellhead Protection Areas, Jessica Moore and others, Kentucky Division of Water, Frankfort, KY
• Status and Early Findings at the Kentucky Horse Park Monitoring Station, James C. Currens and others, Kentucky Geological Survey
• Fluid Evolution in Cambrian-Ordovician Knox Group Reservoirs, Marty Parris and M.W. Bradley, Kentucky Geological Survey and USGS, Tennessee Water Science Center, Nashville, TN
• Simulating Long-Term Fate of CO₂ for a Western …

Session 2b, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• Agriculture Producer Responses to Government-Funded Conservation Programs to Address Water Quality, Wuyang Hu and others, Dept of Agricultural Economics, UK
• Abatement Costs for Agricultural Non-Point Source Polluters, Jack Schieffer and others, Dept of Agricultural Economics, UK
• Point Source Polluters in the Kentucky River Watershed and the Potential for Water Quality Trading, Ron Childress and others, Dept of Agricultural Economics, UK
• Point Source Abatement Costs and Preferences for Trading Market Mechanisms in the Kentucky River Watershed, Andrew McLaughlin and others, Dept of Agricultural Economics, UK

Session 2a, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• The Potential for Using a P Loss Model to Improve the Accuracy of the Kentucky Phosphorus Index, Carl H. Bolster, USDA-ARS, Bowling Green, KY
• Additive State Space Model – A Promising Approach to Water- Quality-Related Treatment Experiments in Heterogeneous Landscapes, Ole Wendroth, Dept of Plant and Soil Sciences, UK
• Development and Application of Numeric Interpretations of Kentucky’s Narrative Water Quality Standards for Nutrients, Lara Panayotoff, Kentucky Division of Water, Frankfort, KY
• Arsenic Removal in Reactor Systems, Aniruddha Dastidar and Y.T. Wang, Watershed Management Branch and Dept of Civil Engineering, UK
• Trends in Water Quality Issues for …

Session 1c, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• The Effects of Prescribed Fire on Amphibian and Reptile Diversity in an Oak-Grassland Restoration Area, Robert Knopp and Howard Whiteman, Dept Biological Sciences and Watershed Studies, Murray State University
• Results of a Data Evaluation to Establish Priority Remediation Areas for Dry Weather Fecal Contamination in a Karst Influenced Watershed, Steve Evans and others, Third Rock Consultants, Lexington, KY
• Development of In-House Methods for High-Throughput DNA Extraction, Kimberly L. Cook and LorraBelle Hill, USDA-ARS, Bowling Green, KY
• Validation of the Sanitary Category Value Model (SCV) for the Identification of Leaking Sewer Lines: A Study of the West Hickman …

Session 1b, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• University – Habitat for Humanity Green Infrastructure Demonstration Project, Nancy Givens and Terry Wilson, WKU Center for Environmental Education and Sustainability, Bowling Green, KY
• Effectiveness of Pollutant Removal in the McConnell Springs Stormwater Quality Wetland Pond and the Gainesway Pond Retrofit Project, Year Two, David J. Price and Susan L. Plueger, Lexington-Fayette Urban County Government
• Coca-Cola Stormwater Replenish Project, Eric Dawalt and Russ Turpin, Ridegewater, LLC and EcoGro, Lexington, KY
• ITEST and LFUCG Stormwater Professional Development, Brian Radcliffe and Carol D. Hanley, Tracy Farmer Institute for Sustainability and the Environment, UK

Session 1a, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• A Regionally-Calibrated Critical Flow for Stream Channel Protection, Bob Hawley and others, Sustainable Streams LLC, Louisville, KY
• Monitoring Wetland Restoration Success at North Fork of Irish Creek, Brian C. Reeder, Center for Environmental Education and Institute for Regional Analysis and Public Policy, Morehead State University
• NC2D Open Channel Flow Model: Development and Applications for Stream Restoration Design in Kentucky, Brian J. Belcher, Beaver Creek Hydrology LLC, Lexington, KY
• Using Remote Sensing Tools to Target Stream Protection and Wastewater Treatment BMPs in Rural Kentucky, Catherine Carter and others, Tetra Tech, Research Triangle Park, NC
• Improving Water Quality …

Plenary Session: Water Research Needs In Kentucky, Alan E. Fryar, Peter T. Goodmann, Michael S. Griffin, James A. Kipp

Kentucky Water Resources Annual Symposium

Four panelists were invited to present their visions/predictions of current and future water research needs in Kentucky in an opening plenary session at the 2012 Kentucky Water Resources Annual Symposium. The requested overall general focus was ground water research needs.

Proceedings Of 2012 Kentucky Water Resources Annual Symposium, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

This symposium was planned and conducted as a part of the state water resources research institute annual program that is supported by Grant/Cooperative Agreement Number G11AP20081 from the United States Geological Survey. The contents of this proceedings document and the views and conclusions presented at the symposium are solely the responsibility of the individual authors and presenters and do not necessarily represent the official views of the USGS or of the symposium organizers and sponsors. This publication is produced with the understanding that the United States Government is authorized to reproduce and distribute reprints for government purposes.

Development And Deployment Of A Bioreactor For The Removal Of Sulfate And Manganese From Circumneutral Coal Mine Drainage, C. B. Mastin, J. D. Edwards, Christopher D. Barton, Anastasios D. Karathanasis, Carmen T. Agouridis, Richard C. Warner

Forestry and Natural Resources Faculty Publications

Surface mining, in the form of contour mining and mountain-top removal, is a common means for retrieving coal in the Appalachian Coal Belt region of Kentucky. Overburden or excess spoil generated by these two methods is placed in valley fills. Traditionally Constructed fills have been shown to adversely impact headwater ecosystems via stream burial and through alterations to the hydrology, sediment supply, water quality and biological composition of downstream reaches. Mine drainages emanating from the toe of valley fills often contain elevated levels of total dissolved solids and heavy metals. Drainage chemistry from Guy Cove, a valley fill located in …

Automated System To Improve Levelness Of Reconstructed Soil, Venkata Srikiran Bodapati, Larry G. Wells

Biosystems and Agricultural Engineering Faculty Publications

Extraction of coal, ores, and minerals from the earth by surface mining has occurred for many years and has always presented a significant challenge with regard to restoration of productive soil to mined areas. Federal and state regulations require that land should be returned to pre-mine productivity or reclaimed as per specific standards following mining. Excessive compaction of reconstructed soil caused by traffic of heavy earth moving equipment has been an enduring challenge regarding successful restoration of soil. A mechanical system was previously designed and developed to reconstruct soil to a depth of 1.22 m (48 in.) while completely avoiding …

Modeling Of Heat Transfer Attenuation By Ablative Gases During The Stardust Re-Entry, Alexandre Martin, Iain D. Boyd

Mechanical Engineering Faculty Publications

The great majority of modern space vehicles designed for planetary exploration use ablative materials to protect the payload against the high heating environment experienced during re-entry. In order to properly model and predict the aerothermal environment of the vehicle, it is imperative to account for the gases produced by ablation processes. In the case of charring ablators, where an inner resin is pyrolyzed at a relatively low temperature, the composition of the gas expelled into the boundary layer is complex and may lead to thermal chemical reactions that cannot be captured with simple flow chemistry models. In order to obtain …

Effect Of Applied Magnetic Field On Shock Boundary Layer Interaction, Ovais U. Khan, Alexandre Martin

Mechanical Engineering Faculty Publications

The governing magneto-hydrodynamic (MHD) equations contain classical fluid dynamics equations along with coupled Maxwell’s magnetic induction equations. These equations model both advection and diffusion effects of electromagnetic field. However, available literature indicates that some previous investigations neglect the diffusion of magnetic field and considered only ideal MHD equations for modeling a typical MHD problem. In this work, the effects of magnetic field diffusion term also known as viscous magnetic term have been investigated over flow structure. Low magnetic Reynolds number approximation and ideal full MHD set of equations have been considered and solved using a four-stage modified Runge-Kutta scheme augmented …

Prescribed Grazing On Pasturelands, Lynn E. Sollenberger, Carmen T. Agouridis, Eric S. Vanzant, Alan J. Franzluebbers, Lloyd B. Owens

Biosystems and Agricultural Engineering Faculty Publications

No abstract provided.

Kentucky Water Resources Research Institute Annual Technical Report Fy 2011, Kentucky Water Resources Research Institute, University Of Kentucky

KWRRI Annual Technical Reports (USGS’s 104b Grant Program)

The FY2011 Annual Technical Report for Kentucky consolidates reporting requirements for the Section 104(b) base grant award into a single document that includes; 1) a synopsis of each research project that was conducted during the period, 2) citations for related publications, reports, and presentations, 3) a description of information transfer activities, 4) a summary of student support during the reporting period, and 5) notable awards and achievements during the year.

Project 2011KY166B (Sewage to fertilizer: a proposed solution to water pollution) was not initiated because the principal investigator (Dr. Rebecca Evans Kelley) resigned from the Department of Biological Sciences at …

Multihierarchical Documents And Fine-Grained Access Control, Neil Moore

Theses and Dissertations--Computer Science

This work presents new models and algorithms for creating, modifying, and controlling access to complex text. The digitization of texts opens new opportunities for preservation, access, and analysis, but at the same time raises questions regarding how to represent and collaboratively edit such texts. Two issues of particular interest are modelling the relationships of markup (annotations) in complex texts, and controlling the creation and modification of those texts. This work addresses and connects these issues, with emphasis on data modelling, algorithms, and computational complexity; and contributes new results in these areas of research.

Although hierarchical models of text and markup …

Bifunctional Bisphosphonates For Delivering Biomolecules To Bone, Jivan N. Yewle

Theses and Dissertations--Chemistry

Active targeting with controlled delivery of therapeutic agents to bone is an ideal approach for treatment of several bone diseases. Since bisphosphonates (BPs) are known to have high affinity to bone mineral and are being widely used in treatment of osteoporosis, they are well-suited for drug targeting to bone. For this purpose, bifunctional hydrazine-bisphosphonates (HBPs) with spacers of various lengths and lipophilicity were synthesized and studied. Crystal growth inhibition assays demonstrated that the HBPs with shorter spacers bound more strongly to bone mineral, hydroxyapatite (HA), than did alendronate. HBPs were also demonstrated to be non-toxic to MC3T3-E1 pre-osteoblasts. The targeted …

Investigations Of Oxidative Stress Effects And Their Mechanisms In Rat Brain After Systemic Administration Of Ceria Engineered Nanomaterials, Sarita S. Hardas

Theses and Dissertations--Chemistry

Advancing applications of engineered nanomaterials (ENM) in various fields create the opportunity for intended (e.g. drug and gene delivery) or unintended (e.g. occupational and environmental) exposure to ENM. However, the knowledge of ENM-toxicity is lagging behind their application development. Understanding the ENM hazard can help us to avoid potential human health problems associated with ENM applications as well as to increase their public acceptance. Ceria (cerium [Ce] oxide) ENM have many current and potential commercial applications. Beyond the traditional use of ceria as an abrasive, the scope of ceria ENM applications now extends into fuel cell manufacturing, diesel fuel additives …