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Full-Text Articles in Physical Sciences and Mathematics

Effect Of Substrate Composition And Alignment On Corneal Cell Phenotype, Donna Phu '09, Lindsay S. Wray '08, Robert V. Warren '10, Richard C. Haskell, Elizabeth J. Orwin Jan 2011

Effect Of Substrate Composition And Alignment On Corneal Cell Phenotype, Donna Phu '09, Lindsay S. Wray '08, Robert V. Warren '10, Richard C. Haskell, Elizabeth J. Orwin

All HMC Faculty Publications and Research

Corneal blindness is a significant problem treated primarily by corneal transplants. Donor tissue supply is low, creating a growing need for an alternative. A tissue-engineered cornea made from patient-derived cells and biopolymer scaffold materials would be widely accessible to all patients and would alleviate the need for donor sources. Previous work in this lab led to a method for electrospinning type I collagen scaffolds for culturing corneal fibroblasts ex vivo that mimics the microenvironment in the native cornea. This electrospun scaffold is composed of small-diameter, aligned collagen fibers. In this study, we investigate the effect of scaffold nanostructure and composition …


Evidence Of The Harmonic Faraday Instability In Ultrasonic Atomization Experiments With A Deep, Inviscid Fluid, Andrew P. Higginbotham '09, Aaron Guillen '11, Nathan C. Jones '10, Thomas D. Donnelly, Andrew J. Bernoff Jan 2011

Evidence Of The Harmonic Faraday Instability In Ultrasonic Atomization Experiments With A Deep, Inviscid Fluid, Andrew P. Higginbotham '09, Aaron Guillen '11, Nathan C. Jones '10, Thomas D. Donnelly, Andrew J. Bernoff

All HMC Faculty Publications and Research

A popular method for generating micron-sized aerosols is to submerge ultrasonic (ω~MHz) piezoelectric oscillators in a water bath. The submerged oscillator atomizes the fluid, creating droplets with radii proportional to the wavelength of the standing wave at the fluid surface. Classical theory for the Faraday instability predicts a parametric instability driving a capillary wave at the subharmonic (ω/2) frequency. For many applications it is desirable to reduce the size of the droplets; however, using higher frequency oscillators becomes impractical beyond a few MHz. Observations are presented that demonstrate that smaller droplets may also be created by …


Stability And Dynamics Of Self-Similarity In Evolution Equations, Andrew J. Bernoff, Thomas P. Witelski Jan 2010

Stability And Dynamics Of Self-Similarity In Evolution Equations, Andrew J. Bernoff, Thomas P. Witelski

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A methodology for studying the linear stability of self-similar solutions is discussed. These fundamental ideas are illustrated on three prototype problems: a simple ODE with finite-time blow-up, a second-order semi-linear heat equation with infinite-time spreading solutions, and the fourth-order Sivashinsky equation with finite-time self-similar blow-up. These examples are used to show that self-similar dynamics can be studied using many of the ideas arising in the study of dynamical systems. In particular, the use of dimensional analysis to derive scaling invariant similarity variables is discussed, as well as the role of symmetries in the context of stability of self-similar dynamics. The …


Local Versus Global Search In Channel Graphs, A.H. Hunter, Nicholas Pippenger Jan 2010

Local Versus Global Search In Channel Graphs, A.H. Hunter, Nicholas Pippenger

All HMC Faculty Publications and Research

Previous studies of search in channel graphs has assumed that the search is global; that is, that the status of any link can be probed by the search algorithm at any time. We consider for the first time local search, for which only links to which an idle path from the source has already been established may be probed. We show that some well known channel graphs may require exponentially more probes, on the average, when search must be local than when it may be global.


E-Transcript Web Services System Supporting Dynamic Conversion Between Xml And Edi, Myungjae Kwak '11, Woohyun Kang '14, Gondy Leroy, Samir Chatterjee Aug 2008

E-Transcript Web Services System Supporting Dynamic Conversion Between Xml And Edi, Myungjae Kwak '11, Woohyun Kang '14, Gondy Leroy, Samir Chatterjee

CGU Faculty Publications and Research

As XML becomes a standard for communications between distributed heterogeneous machines, many schools plan to implement Web Services systems using the XML e-transcript (electronic transcript) standard. We propose a framework that supports both XML e-transcript Web Services and existing EDI e-transcript systems. The framework uses the workflow engine to exploit the benefits of workflow management mechanisms. The workflow engine manages the e-transcript business process by enacting and completing the tasks and sub-processes within the main business process. We implemented the proposed framework by using various open source projects including Java, Eclipse, and Apache Software Foundation’s Web Services projects. Compared with …


Computer Modeling And Analysis Of Thermal Link Performance For An Optical Refrigerator, Kevin Byram, David Mar, John Parker, Steven Von Der Porten, John Hankinson, Chris Lee, Kai Mayeda, Richard C. Haskell, Qimin Yang, Scott R. Greenfield, Richard I. Epstein Feb 2008

Computer Modeling And Analysis Of Thermal Link Performance For An Optical Refrigerator, Kevin Byram, David Mar, John Parker, Steven Von Der Porten, John Hankinson, Chris Lee, Kai Mayeda, Richard C. Haskell, Qimin Yang, Scott R. Greenfield, Richard I. Epstein

All HMC Faculty Publications and Research

We have used the thermal modeling tool in COMSOL Multiphysics to investigate factors that affect the thermal performance of the optical refrigerator. Assuming an ideal cooling element and a non-absorptive dielectric trapping mirror, the three dominant heating factors are blackbody radiation from the surrounding environment, conductive heat transfer through mechanical supports, and the absorption of fluorescent photons transmitted through the thermal link. Laboratory experimentation coupled with computer modeling using Code V optical software have resulted in link designs capable of reducing the transmission to 0.04% of the fluoresced photons emitted toward the thermal link. The ideal thermal link will have …


A Model For Rolling Swarms Of Locusts, Chad M. Topaz, Andrew J. Bernoff, Sheldon Logan '06, Wyatt Toolson '07 Jan 2008

A Model For Rolling Swarms Of Locusts, Chad M. Topaz, Andrew J. Bernoff, Sheldon Logan '06, Wyatt Toolson '07

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We construct an individual-based kinematic model of rolling migratory locust swarms. The model incorporates social interactions, gravity, wind, and the effect of the impenetrable boundary formed by the ground. We study the model using numerical simulations and tools from statistical mechanics, namely the notion of H-stability. For a free-space swarm (no wind and gravity), as the number of locusts increases, the group approaches a crystalline lattice of fixed density if it is H-stable, and in contrast becomes ever denser if it is catastrophic. Numerical simulations suggest that whether or not a swarm rolls depends on the statistical mechanical properties of …


Women And Technology: Reversing The Trends Of Attrition And Obtaining A Balance, Gondy Leroy, Kristin M. Tolle, Linda Perkins Jan 2008

Women And Technology: Reversing The Trends Of Attrition And Obtaining A Balance, Gondy Leroy, Kristin M. Tolle, Linda Perkins

CGU Faculty Publications and Research

Many reports and technical news bulletins presented by organizations such as the National Science Foundation (NSF), the Institute of Electrical and Electronics Engineers (IEEE), the Association for Computing Machinery (ACM), and the National Center for Women & Information Technology (NCWIT) highlight that few female and minority college students are choosing science, technology, engineering, and math (STEM) fields of study or careers. For those who choose STEM fields, attrition both during education and in the workplace is pervasive. NSF reports in its 2006 Science Indicators that women account for only 27% of the bachelor’s degrees in computer sciences. And although the …


Certifications Offered By Cost Estimating Organizations, Donald S. Remer, Karen M. Ahle, Kevin J. Alley, John Silny, Karen Hsin Oct 2006

Certifications Offered By Cost Estimating Organizations, Donald S. Remer, Karen M. Ahle, Kevin J. Alley, John Silny, Karen Hsin

All HMC Faculty Publications and Research

There has been an increasing trend in professional and engineering circles to place greater emphasis on official credentials. These credentials commonly come in the form of certificates – documented recognition by a professional body that an engineer or other professional has the qualifications and technical knowledge to be a practitioner in that field. These certificates are somewhat analogous to merit badges in scouting – the certification is evidence that the holder has a certain minimum level of competence in the subject area. This review will help you decide what certifications are applicable to you and the requirements to obtain a …


Using Ultrasonic Atomization To Produce An Aerosol Of Micron-Scale Particles, Thomas D. Donnelly, J. Hogan '03, A. Mugler '04, M. Schubmehl '02, N. Schommer '04, Andrew J. Bernoff, S. Dasnurkar, T. Ditmire Nov 2005

Using Ultrasonic Atomization To Produce An Aerosol Of Micron-Scale Particles, Thomas D. Donnelly, J. Hogan '03, A. Mugler '04, M. Schubmehl '02, N. Schommer '04, Andrew J. Bernoff, S. Dasnurkar, T. Ditmire

All HMC Faculty Publications and Research

A device that uses ultrasonic atomization of a liquid to produce an aerosol of micron-scale droplets is described. This device represents a new approach to producing targets relevant to laser-driven fusion studies, and to rare studies of nonlinear optics in which wavelength-scale targets are irradiated. The device has also made possible tests of fluid dynamics models in a novel phase space. The distribution of droplet sizes produced by the device and the threshold power required for droplet production are shown to follow scaling laws predicted by fluid dynamics.


Non-Verbal Communication With Autistic Children Using Digital Libraries, Gondy A. Leroy, John Huang '05, Serena Chuang '05, Marjorie H. Charlop Jan 2005

Non-Verbal Communication With Autistic Children Using Digital Libraries, Gondy A. Leroy, John Huang '05, Serena Chuang '05, Marjorie H. Charlop

CGU Faculty Publications and Research

Autism spectrum disorder (ASD) has become one of the most prevalent mental disorders over the last few years and its prevalence is still growing. The disorder is characterized by a wide variety of symptoms such as lack of social behavior, extreme withdrawal, and problems communicating. Because of the diversity in symptoms and the wide variety in severity for those, each autistic child has different needs and requires individualized therapy. This leads to long waiting lists for therapy.


Immunogold Labeling To Enhance Contrast In Optical Coherence Microscopy Of Tissue Engineered Corneal Constructs, Chris B. Raub, Elizabeth J. Orwin, Richard C. Haskell Sep 2004

Immunogold Labeling To Enhance Contrast In Optical Coherence Microscopy Of Tissue Engineered Corneal Constructs, Chris B. Raub, Elizabeth J. Orwin, Richard C. Haskell

All HMC Faculty Publications and Research

Our lab has used an optical coherence microscope (OCM) to assess both the structure of tissue-engineered corneal constructs and their transparency. Currently, we are not able to resolve cells versus collagen matrix material in the images produced. We would like to distinguish cells in order to determine if they are viable while growing in culture and also if they are significantly contributing to the light scattering in the tissue. In order to do this, we are currently investigating the use of immunogold labeling. Gold nanoparticles are high scatterers and can create contrast in images. We have conjugated gold nanoparticles to …


Model Updating By Adding Known Masses And Stiffnesses, Philip D. Cha, Lisette G. De Pillis Jan 1999

Model Updating By Adding Known Masses And Stiffnesses, Philip D. Cha, Lisette G. De Pillis

All HMC Faculty Publications and Research

New approaches are developed to update the analytical mass and stiffness matrices of a system. By adding known masses to the structure of interest, measuring the modes of vibration of this mass-modified system, and finally using this set of new data in conjunction with the initial modal survey, the mass matrix of the structure can be corrected. A similar approach can also be used to update the stiffness matrix of the system by attaching known stiffnesses. Manipulating the mass and stiffness correction matrices into vector forms, the connectivity information can be enforced, thereby preserving the physical configuration of the system, …


Design And Design Centers In Engineering Education, Clive L. Dym Jan 1998

Design And Design Centers In Engineering Education, Clive L. Dym

All HMC Faculty Publications and Research

This paper is intended to be the opening salvo of the workshop, Computing Futures in Engineering Design (Dym, 1997). Thus, I want to take this privileged moment to ask you to think with me about the role of design in engineering. In particular, I want to reflect upon how design is articulated and how design is taught; about the role of design in engineering education and in the practice of engineering; and about the role that could be played locally and, perhaps, nationally by a center devoted to design education. Because I teach here at Harvey Mudd College (HMC), …


The Steady Boundary Layer Due To A Fast Vortex, Andrew J. Bernoff, Harald J. H. M. Van Dongen, Seth Lichter Jan 1996

The Steady Boundary Layer Due To A Fast Vortex, Andrew J. Bernoff, Harald J. H. M. Van Dongen, Seth Lichter

All HMC Faculty Publications and Research

A point vortex located above and convected parallel to a wall is an important model of the process by which a boundary layer becomes unstable due to external disturbances. Often it has been assumed that the boundary layer due to the passage of the vortex is inherently unsteady. Here we show that for a vortex convected by a uniform shear flow, there is a steady solution when the speed of the vortex cv is sufficiently fast. The existence of the steady solution is demonstrated analytically in the limit of large vortex velocity (cv→∞) and numerically …


Intraocular Lens Case Designs, Donald S. Remer, Stephen S. Davis, Michael Bak '95, Ken Kalafus, Ilan Sabar, Khannan Suntharam, William Washington, Yu-Tung Wong Jan 1996

Intraocular Lens Case Designs, Donald S. Remer, Stephen S. Davis, Michael Bak '95, Ken Kalafus, Ilan Sabar, Khannan Suntharam, William Washington, Yu-Tung Wong

All HMC Faculty Publications and Research

IOLAB Corporation makes two types of intraocular lenses for the replacement of cataracts: one from polymethyl methacrylate (PMMA) and a newer one from silicone. IOLAB ships the lens to the doctor in a two-piece case made from polycarbonate. At a price of $0.53 per case, IOLAB spends about $270,000 per year on lens cases (based on 1994 purchases of 500,000 cases). IOLAB asked us to reduce the cost of the existing lens case and to design a new case to protect and fold the silicone lens. We designed three items.


Distortion And Evolution Of A Localized Vortex In An Irrotational Flow, Joseph F. Lingevitch, Andrew J. Bernoff May 1995

Distortion And Evolution Of A Localized Vortex In An Irrotational Flow, Joseph F. Lingevitch, Andrew J. Bernoff

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This paper examines the interaction of an axisymmetric vortex monopole, such as a Lamb vortex, with a background irrotational flow. At leading order, the monopole is advected with the background flow velocity at the center of vorticity. However, inhomogeneities of the flow will cause the monopole to distort. It is shown that a shear‐diffusion mechanism, familiar from the study of mixing of passive scalars, plays an important role in the evolution of the vorticity distribution. Through this mechanism, nonaxisymmetric vorticity perturbations which do not shift the center of vorticity are homogenized along streamlines on a Re1/3 time scale, much faster …


Rapid Relaxation Of An Axisymmetric Vortex, Andrew J. Bernoff, Joseph F. Lingevitch Nov 1994

Rapid Relaxation Of An Axisymmetric Vortex, Andrew J. Bernoff, Joseph F. Lingevitch

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In this paper it is argued that a two‐dimensional axisymmetric large Reynolds number (Re) monopole when perturbed will return to an axisymmetric state on a time scale (Re1/3) that is much faster than the viscous evolution time scale (Re). It is shown that an arbitrary perturbation can be broken into three pieces; first, an axisymmetric piece corresponding to a slight radial redistribution of vorticity; second, a translational piece which corresponds to a small displacement of the center of the original vortex; and finally, a nonaxisymmetric perturbation which decays on the Re1/3 time scale due to a shear/diffusion …


Tissue Characterization And Imaging Using Photon Density Waves, Lars O. Svaasand, Bruce J. Tromberg, Richard C. Haskell, Tsong-Tseh Tsay, Michael W. Berns Feb 1993

Tissue Characterization And Imaging Using Photon Density Waves, Lars O. Svaasand, Bruce J. Tromberg, Richard C. Haskell, Tsong-Tseh Tsay, Michael W. Berns

All HMC Faculty Publications and Research

The optical properties of brain tissues have been evaluated by measuring the phase velocity and attenuation of harmonically modulated light. The phase velocity for photon density waves at 650-nm wavelength has been found to be in the range of 5 to 12% of the corresponding velocity in a nonscattering medium, and the optical penetration depth was in the range 2.9 to 5.2 mm. These results are used to predict the resolution of optical imaging of deep tissue structures by diffusely propagating incoherent photons. The results indicate that structures of a few millimeters in linear dimension can be identified at 10 …


Viscous Cross-Waves: An Analytical Treatment, Andrew J. Bernoff, L. P. Kwok, Seth Lichter Jan 1989

Viscous Cross-Waves: An Analytical Treatment, Andrew J. Bernoff, L. P. Kwok, Seth Lichter

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Viscous effects on the excitation of cross‐waves in a semi‐infinite box of finite depth and width are considered. A formalism using matched asymptotic expansions and an improved method of computing the solvability condition is used to derive the relative contributions of the free‐surface, sidewall, bottom, and wavemaker viscous boundary layers. This analysis yields an expression for the damping coefficient previously incorporated on heuristic grounds. In addition, three new contributions are found: a viscous detuning of the resonant frequency, a slow spatial variation in the coupling to the progressive wave, and a viscous correction to the wavemaker boundary condition. The wavemaker …


Stability Of Steady Cross-Waves: Theory And Experiment, Seth Lichter, Andrew J. Bernoff Mar 1988

Stability Of Steady Cross-Waves: Theory And Experiment, Seth Lichter, Andrew J. Bernoff

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A bifurcation analysis is performed in the neighborhood of neutral stability for cross waves as a function of forcing, detuning, and viscous damping. A transition is seen from a subcritical to a supercritical bifurcation at a critical value of the detuning. The predicted hysteretic behavior is observed experimentally. A similarity scaling in the inviscid limit is also predicted. The experimentally observed bifurcation curves agree with this scaling.


Measuring R And D Productivity, Richard A. Pappas, Donald S. Remer May 1985

Measuring R And D Productivity, Richard A. Pappas, Donald S. Remer

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Measuring the productivity of an R&D organization is extremely tricky. Productivity is usually defined as a ratio of an output, like number of cars produced on an assembly line, to an input, like the wages paid the workers. While R&D may have a measurable input, the output is often intangible and difficult to quantify. This is further complicated because the return from an R&D department may not be realized for one or two decades,which means the time lag is much higher than in factory measurements. Furthermore, many researchers believe that this kind of measurement may be counterproductive,since the mere act …


Response Of Lithographic Mask Structures To Repetitively Pulsed X-Rays: Thermal Stress Analysis, A. Ballantyne, H.A. Hyman, Clive L. Dym, R.C. Southworth Jan 1985

Response Of Lithographic Mask Structures To Repetitively Pulsed X-Rays: Thermal Stress Analysis, A. Ballantyne, H.A. Hyman, Clive L. Dym, R.C. Southworth

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This paper examines the effects of thermal loading and time history upon the thermal stresses developed in lithographic mask structures as would be expected under irradiation by intense soft x rays. The objective of this work was to examine the phenomenology of the interaction and to evaluate the limits placed upon mask dosage. The mechanics of mask failure are examined in terms of single pulse and cumulative, or fatigue, effects. A number of prototypical mask structures are investigated, which show that the application of intense pulsed sources to x‐ray lithography does not reduce the potential utility of the techique. However, …


Response Of Lithographic Mask Structures To Repetitively Pulsed X-Rays: Dynamic Response, Clive L. Dym, A. Ballantyne Jan 1985

Response Of Lithographic Mask Structures To Repetitively Pulsed X-Rays: Dynamic Response, Clive L. Dym, A. Ballantyne

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This paper addresses the issue of the dynamic response of thin lithographic mask structures to thermally induced stress fields. In particular, the impact of repetitively pulsed x‐ray sources are examined: the short duration (1–100 nsec) pulses induce large step changes in mask temperatures, which can, in turn, induce a dynamic response. The impact of conductive cooling of the mask is to reduce the repetitively pulsed problem to a series of isolated nearly identical thermal impulses of duration approximately equal to the cooling time. The importance of self‐weight and prestress is examined, and an analysis of the nonlinear dynamic response to …


A Theoretical Model For Gas Separation In A Glow Discharge: Cataphoresis, Fredrick H. Shair, Donald S. Remer Nov 1968

A Theoretical Model For Gas Separation In A Glow Discharge: Cataphoresis, Fredrick H. Shair, Donald S. Remer

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A theoretical model for transient and steady-state cataphoresis is developed starting with the macroscopic equations of continuity. After a brief breakdown period, the impurity ions are assumed to be closely coupled with their neutral counterparts. The basic assumptions in the model are that after breakdown, the level of ionization of the impurity, and the axial electric field remain constant; it is demonstrated that under these conditions a system involving rapid ionization-recombination reactions is equivalent to a system in which no reaction occurs, but in which the "effective'' ion mobility is a product of the true ion mobility and the fraction …