Physical Sciences and Mathematics Commons^™

Modeling And Evaluating Cost-Effectiveness Of Host-Microbiome Investigations, Renuka Panchagavi

Dissertations

Cost-effectiveness modeling accounts for how expenditures impact outcomes and is an appropriate step towards efficacy of the different methods used for modeling the dynamics of microbial communities. This will help to identify challenging aspects of microbiome studies and the associated costs, including the major differences in research designs (cross-sectional or time series-based) used for conducting such studies. The two major stages of our investigation were to first collect and model cost variable data for microbiome investigations, and then to evaluate how trade-offs related to sample size and expenditures impact investigational outcomes. We screened different potential sources of data for microbiome …