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Full-Text Articles in Physical Sciences and Mathematics
Hybrid Spr Algorithm To Select Predictive Genes For Effectual Cancer Classification, Aruna Sundaram, Nandakishore Lellapalli Venkata, Rajagopalan Sarukai Parthasarathy
Hybrid Spr Algorithm To Select Predictive Genes For Effectual Cancer Classification, Aruna Sundaram, Nandakishore Lellapalli Venkata, Rajagopalan Sarukai Parthasarathy
Turkish Journal of Electrical Engineering and Computer Sciences
Designing an automated system for classifying DNA microarray data is an extremely challenging problem because of its high dimension and low amount of sample data. In this paper, a hybrid statistical pattern recognition algorithm is proposed to reduce the dimensionality and select the predictive genes for the classification of cancer. Colon cancer gene expression profiles having 62 samples of 2000 genes were used for the experiment. A gene subset of 6 highly informative genes was selected by the algorithm, which provided a classification accuracy of 93.5%.
Shifted-Modified Chebyshev Filters, Meti̇n Şengül
Shifted-Modified Chebyshev Filters, Meti̇n Şengül
Turkish Journal of Electrical Engineering and Computer Sciences
This paper introduces a new type of filter approximation method that utilizes shifted-modified Chebyshev filters. Construction of the new filters involves the use of shifted-modified Chebyshev polynomials that are formed using the roots of conventional Chebyshev polynomials. The study also includes 2 tables containing the shifted-modified Chebyshev polynomials and the normalized element values for the low-pass prototype filters up to degree 6. The transducer power gain, group delay, and impulse and step responses of the proposed filters are compared with those of the Butterworth and Chebyshev filters, and a sixth-order filter design example is presented to illustrate the implementation of …