Physical Sciences and Mathematics Commons^™

Weakly Supervised Learning For Multi-Image Synthesis, Muhammad Usman Rafique

Theses and Dissertations--Electrical and Computer Engineering

Machine learning-based approaches have been achieving state-of-the-art results on many computer vision tasks. While deep learning and convolutional networks have been incredibly popular, these approaches come at the expense of huge amounts of labeled data required for training. Manually annotating large amounts of data, often millions of images in a single dataset, is costly and time consuming. To deal with the problem of data annotation, the research community has been exploring approaches that require less amount of labelled data.

The central problem that we consider in this research is image synthesis without any manual labeling. Image synthesis is a classic …

Relation Prediction Over Biomedical Knowledge Bases For Drug Repositioning, Mehmet Bakal

Theses and Dissertations--Computer Science

Identifying new potential treatment options for medical conditions that cause human disease burden is a central task of biomedical research. Since all candidate drugs cannot be tested with animal and clinical trials, in vitro approaches are first attempted to identify promising candidates. Likewise, identifying other essential relations (e.g., causation, prevention) between biomedical entities is also critical to understand biomedical processes. Hence, it is crucial to develop automated relation prediction systems that can yield plausible biomedical relations to expedite the discovery process. In this dissertation, we demonstrate three approaches to predict treatment relations between biomedical entities for the drug repositioning task …