Physical Sciences and Mathematics Commons^™

Mathematical Model For Osteosarcoma Progression And Treatments, Trang M. Le

Doctoral Dissertations

Cancer is a complex disease where every tumor has its own characteristics, and thus different tumors may respond differently to the same treatments. Osteosarcoma, which is a rare type of cancer with poor prognosis, is especially characterized by its high heteogeneity. Therefore, it is important to study the progression of osteosarcoma tumors in different groups of patients with distinct characteristics. The immune system has been reported to play an important role in the development of various cancers with some immune cells having anti-tumor effects and others having pro-tumor effects. With recent advances in digital cytometry methods, which are techniques to …