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Articles 1 - 6 of 6
Full-Text Articles in Physical Sciences and Mathematics
Non-Inferiority Testing: Kernel Estimation And Overlap Measure, Larie C. Ward
Non-Inferiority Testing: Kernel Estimation And Overlap Measure, Larie C. Ward
Electronic Theses and Dissertations
In non-inferiority testing, the decision of whether a proposed treatment is non-inferior to a reference treatment depends on model assumptions and choices of acceptable tolerance limits. Here, we consider a method that employs kernels to estimate the probability density functions of both the experimental and reference populations from two independent samples. Based on these densities, we introduce a quantity called the overlap coefficient or overlap measure. A bootstrap technique is helpful in exploring the distribution and variance empirically. We derive the distribution of this measure and define a hypothesis test that can be applied to the non-inferiority setting under some …
Public Perception Of Different Planting Techniques Using Augmented Reality, Sultana Quader Tania
Public Perception Of Different Planting Techniques Using Augmented Reality, Sultana Quader Tania
Electronic Theses and Dissertations
The objective of this study was to measure public perception of the different planting techniques (block and matrix), which are used at visitor information centers (VICs) and other rights of way (ROW) areas. The main factors that affect public perception of planting techniques were identified through an extensive literature review and qualitative survey from four welcome centers in the state of Georgia. The ranking of those indicators, based on public preferences, was discovered through a quantitative survey. During the first phase of the quantitative survey, images of block and matrix were used. An iOS-based user-friendly and cost-effective augmented reality (AR) …
Safety Constraint Optimization Of Combination Drug Therapy In Hypertension Clinical Trials, Victor Chukwu
Safety Constraint Optimization Of Combination Drug Therapy In Hypertension Clinical Trials, Victor Chukwu
Electronic Theses and Dissertations
In Clinical Practice, combination drug therapy has become common in treating many disease conditions. The purpose of these combinations is often to ensure optimal efficacy and to reduce adverse effects that may arise from monotherapy. Clinical trials have also been conducted to ensure efficacy and safety of these combinations before they are introduced into the market. However, adverse effects still occur with combination therapies. The objective of this study is to (1) To determine a region of optimum doses of Drug A and Drug B in combination while focusing on efficacy alone (2) To determine a region of optimum doses …
A Markov Decision Process Approach To Adaptive Contact Strategies, Artur Grygorian
A Markov Decision Process Approach To Adaptive Contact Strategies, Artur Grygorian
Electronic Theses and Dissertations
In the field of survey methodology, optimizing contact strategies helps organizations increase response rates using their allocated budget. Markov Decision Processes (MDP) are widely used to model decision-making strategies in situations where the outcomes have a random component. In this research, we use MDPs and adaptive sampling techniques to construct a strategy that, based on target audience characteristics, suggests the best contact policy. The data we use comes from the First Destination Survey conducted by the Office of Career Services at Georgia Southern University. The constructed model is quite flexible and can be used by other organizations to optimize their …
Statistical Analysis Of Unreplicated Factorial Designs Using Contrasts, Meixi Yang
Statistical Analysis Of Unreplicated Factorial Designs Using Contrasts, Meixi Yang
Electronic Theses and Dissertations
Factorial designs can have a large number of treatments due to the number of factors and the number of levels of each factor. The number of experimental units required for a researcher to conduct a $k$ factorial experiment is at least the number of treatments. For such an experiment, the total number of experimental units will also depend on the number of replicates for each treatment. The more experimental units used in a study the more the cost to the researcher. The minimum cost is associated with the case in which there is one experimental unit per treatment. That is, …
Comparing K Population Means With No Assumption About The Variances, Tony Yaacoub
Comparing K Population Means With No Assumption About The Variances, Tony Yaacoub
Electronic Theses and Dissertations
In the analysis of most statistically designed experiments, it is common to assume equal variances along with the assumptions that the sample measurements are independent and normally distributed. Under these three assumptions, a likelihood ratio test is used to test for the difference in population means. Typically, the assumption of independence can be justified based on the sampling method used by the researcher. The likelihood ratio test is robust to the assumption of normality. However, the equality of variances is often difficult to justify. It has been found that the assumption of equal variances cannot be made even after transforming …