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Full-Text Articles in Physical Sciences and Mathematics

A Novel Density Peak Clustering Algorithm Based On Squared Residual Error, Milan Parmar, Di Wang, Ah-Hwee Tan, Chunyan Miao, Jianhua Jiang, You Zhou Dec 2017

A Novel Density Peak Clustering Algorithm Based On Squared Residual Error, Milan Parmar, Di Wang, Ah-Hwee Tan, Chunyan Miao, Jianhua Jiang, You Zhou

Research Collection School Of Computing and Information Systems

The density peak clustering (DPC) algorithm is designed to quickly identify intricate-shaped clusters with high dimensionality by finding high-density peaks in a non-iterative manner and using only one threshold parameter. However, DPC has certain limitations in processing low-density data points because it only takes the global data density distribution into account. As such, DPC may confine in forming low-density data clusters, or in other words, DPC may fail in detecting anomalies and borderline points. In this paper, we analyze the limitations of DPC and propose a novel density peak clustering algorithm to better handle low-density clustering tasks. Specifically, our algorithm …


A Novel Approach For Classifying Gene Expression Data Using Topic Modeling, Soon Jye Kho, Himi Yalamanchili, Michael L. Raymer, Amit Sheth Jan 2017

A Novel Approach For Classifying Gene Expression Data Using Topic Modeling, Soon Jye Kho, Himi Yalamanchili, Michael L. Raymer, Amit Sheth

Kno.e.sis Publications

Understanding the role of differential gene expression in cancer etiology and cellular process is a complex problem that continues to pose a challenge due to sheer number of genes and inter-related biological processes involved. In this paper, we employ an unsupervised topic model, Latent Dirichlet Allocation (LDA) to mitigate overfitting of high-dimensionality gene expression data and to facilitate understanding of the associated pathways. LDA has been recently applied for clustering and exploring genomic data but not for classification and prediction. Here, we proposed to use LDA inclustering as well as in classification of cancer and healthy tissues using lung cancer …


Xic Clustering By Baseyian Network, Kyle J. Handy Jan 2017

Xic Clustering By Baseyian Network, Kyle J. Handy

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.