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Full-Text Articles in Physical Sciences and Mathematics
An Experiment In Integrating Large Biomedical Knowledge Resources With Rdf: Application To Associating Genotype And Phenotype Information, Satya S. Sahoo, Olivier Bodenreider, Kelly Zeng, Amit P. Sheth
An Experiment In Integrating Large Biomedical Knowledge Resources With Rdf: Application To Associating Genotype And Phenotype Information, Satya S. Sahoo, Olivier Bodenreider, Kelly Zeng, Amit P. Sheth
Kno.e.sis Publications
Bridging between genotype and phenotype is generally achieved through the integration of knowledge sources such as Entrez Gene (EG), Online Mendelian Inheritance in Man (OMIM) and the Gene Ontology (GO). Traditionally, such integration implies manual effort or the development of customized software. In this paper, we demonstrate how the Resource Description Framework (RDF) can be used to represent and integrate these resources and support complex queries over the unified resource. We illustrate the effectiveness of our approach by answering a real-world biomedical query linking a specific molecular function, glycosyltransferase, to the disorder congenital muscular dystrophy, which potentially forms a new …
What, Where And When: Supporting Semantic, Spatial And Temporal Queries In A Dbms, Matthew Perry, Amit P. Sheth, Farshad Hakimpour, Prateek Jain
What, Where And When: Supporting Semantic, Spatial And Temporal Queries In A Dbms, Matthew Perry, Amit P. Sheth, Farshad Hakimpour, Prateek Jain
Kno.e.sis Publications
Spatial and temporal data are critical components in many applications. This is especially true in analytical domains such as national security and criminal investigation. The outcome of the analytical process in these applications often hinges on uncovering and analyzing complex relationships between disparate people, places and events. Fundamentally new query operators based on the graph structure of Semantic Web data models, such as semantic associations, are proving useful in these applications. However, these analysis mechanisms are primarily intended for thematic relationships. We describe a framework built around the RDF metadata model for analysis of thematic, spatial and temporal relationships between …