Physical Sciences and Mathematics Commons^™

Estimating Loop Length From Cryoem Images At Medium Resolutions, Andrew Mcknight, Dong Si, Kamal Al Nasr, Andrey Chernikov, Nikos Chrisochoides, Jing He

Computer Science Faculty Research

Background

De novo protein modeling approaches utilize 3-dimensional (3D) images derived from electron cryomicroscopy (CryoEM) experiments. The skeleton connecting two secondary structures such as α-helices represent the loop in the 3D image. The accuracy of the skeleton and of the detected secondary structures are critical in De novo modeling. It is important to measure the length along the skeleton accurately since the length can be used as a constraint in modeling the protein.

Results

We have developed a novel computational geometric approach to derive a simplified curve in order to estimate the loop length along the skeleton. The method …

Multimedia Data Fusion, Shangbo Zhou, Henry Leung, Fenghui Yao

Computer Science Faculty Research

Multimedia data is widely used in the world such as image, video, text, and audio. For obtaining better sensing performance, research on multimedia data fusion (MDF) is active and extensive around the world. In medical systems, a body part could be imaged with different sensors such as computed tomography and magnetic resonance imaging. In video surveillance, the interest is in the identification, recognition, and tracking of people by numerous cameras. All of these cases illustrate the importance of MDF in real-life applications. A number of mathematical methods have been researched in MDF such as statistics, fuzzy mathematical, stochastic differential theory, …