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Full-Text Articles in Physical Sciences and Mathematics

High-Performance Computing Frameworks For Large-Scale Genome Assembly, Sayan Goswami Jun 2019

High-Performance Computing Frameworks For Large-Scale Genome Assembly, Sayan Goswami

LSU Doctoral Dissertations

Genome sequencing technology has witnessed tremendous progress in terms of throughput and cost per base pair, resulting in an explosion in the size of data. Typical de Bruijn graph-based assembly tools demand a lot of processing power and memory and cannot assemble big datasets unless running on a scaled-up server with terabytes of RAMs or scaled-out cluster with several dozens of nodes. In the first part of this work, we present a distributed next-generation sequence (NGS) assembler called Lazer, that achieves both scalability and memory efficiency by using partitioned de Bruijn graphs. By enhancing the memory-to-disk swapping and reducing the …


Statistical Machine Learning Methods For Mining Spatial And Temporal Data, Fei Tan May 2019

Statistical Machine Learning Methods For Mining Spatial And Temporal Data, Fei Tan

Dissertations

Spatial and temporal dependencies are ubiquitous properties of data in numerous domains. The popularity of spatial and temporal data mining has thus grown with the increasing prevalence of massive data. The presence of spatial and temporal attributes not only provides complementary useful perspectives, but also poses new challenges to the representation and integration into the learning procedure. In this dissertation, the involved spatial and temporal dependencies are explored with three genres: sample-wise, feature-wise, and target-wise. A family of novel methodologies is developed accordingly for the dependency representation in respective scenarios.

First, dependencies among discrete, continuous and repeated observations are studied …


Google Trends Data As A Proxy For Interest In Leadership, Finley W. Walker Apr 2019

Google Trends Data As A Proxy For Interest In Leadership, Finley W. Walker

Doctor of Education (Ed.D)

The purpose of this quantitative study was to investigate the observable patterns of online search behavior in the topic of leadership using Google Trends data. Institutions have had a historically difficult time predicting good leadership candidates. Better predictions can be made by using the big data offered by groups such as Google to learn who, where, and when people are interested in leadership. The study utilized descriptive, comparative, and correlative methodologies to study Google users’ interest in leadership from 2004 to 2017. Society has placed great value into leadership throughout history, and though overall interest remains strong, it appears that …


A Data-Driven Approach For Modeling Agents, Hamdi Kavak Apr 2019

A Data-Driven Approach For Modeling Agents, Hamdi Kavak

Computational Modeling & Simulation Engineering Theses & Dissertations

Agents are commonly created on a set of simple rules driven by theories, hypotheses, and assumptions. Such modeling premise has limited use of real-world data and is challenged when modeling real-world systems due to the lack of empirical grounding. Simultaneously, the last decade has witnessed the production and availability of large-scale data from various sensors that carry behavioral signals. These data sources have the potential to change the way we create agent-based models; from simple rules to driven by data. Despite this opportunity, the literature has neglected to offer a modeling approach to generate granular agent behaviors from data, creating …


Privacy Preservation In Social Media Environments Using Big Data, Katrina Ward Jan 2019

Privacy Preservation In Social Media Environments Using Big Data, Katrina Ward

Doctoral Dissertations

"With the pervasive use of mobile devices, social media, home assistants, and smart devices, the idea of individual privacy is fading. More than ever, the public is giving up personal information in order to take advantage of what is now considered every day conveniences and ignoring the consequences. Even seemingly harmless information is making headlines for its unauthorized use (18). Among this data is user trajectory data which can be described as a user's location information over a time period (6). This data is generated whenever users access their devices to record their location, query the location of a point …