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Full-Text Articles in Physical Sciences and Mathematics

Overlap Matrix Completion For Predicting Drug-Associated Indications, Menhyun Yang, Huimin Luo, Yaohang Li, Fang-Xiang Wu, Jianxin Wang Dec 2019

Overlap Matrix Completion For Predicting Drug-Associated Indications, Menhyun Yang, Huimin Luo, Yaohang Li, Fang-Xiang Wu, Jianxin Wang

Computer Science Faculty Publications

Identification of potential drug-associated indications is critical for either approved or novel drugs in drug repositioning. Current computational methods based on drug similarity and disease similarity have been developed to predict drug-disease associations. When more reliable drug- or disease-related information becomes available and is integrated, the prediction precision can be continuously improved. However, it is a challenging problem to effectively incorporate multiple types of prior information, representing different characteristics of drugs and diseases, to identify promising drug-disease associations. In this study, we propose an overlap matrix completion (OMC) for bilayer networks (OMC2) and tri-layer networks (OMC3) to predict potential drug-associated …


Mementomap: An Archive Profile Dissemination Framework, Sawood Alam, Michele C. Weigle, Michael L. Nelson Jun 2019

Mementomap: An Archive Profile Dissemination Framework, Sawood Alam, Michele C. Weigle, Michael L. Nelson

Computer Science Faculty Publications

We introduce MementoMap, a framework to express and disseminate holdings of web archives (archive profiles) by themselves or third parties. The framework allows arbitrary, flexible, and dynamic levels of details in its entries that fit the needs of archives of different scales. This enables Memento aggregators to significantly reduce wasted traffic to web archives.


Impact Of Http Cookie Violations In Web Archives, Sawood Alam, Michele C. Weigle, Michael L. Nelson Jun 2019

Impact Of Http Cookie Violations In Web Archives, Sawood Alam, Michele C. Weigle, Michael L. Nelson

Computer Science Faculty Publications

Certain HTTP Cookies on certain sites can be a source of content bias in archival crawls. Accommodating Cookies at crawl time, but not utilizing them at replay time may cause cookie violations, resulting in defaced composite mementos that never existed on the live web. To address these issues, we propose that crawlers store Cookies with short expiration time and archival replay systems account for values in the Vary header along with URIs.


Ieee Access Special Section Editorial: Wirelessly Powered Networks, And Technologies, Theofanis P. Raptis, Nuno B. Carvalho, Diego Masotti, Lei Shu, Cong Wang, Yuanyuan Yang Jan 2019

Ieee Access Special Section Editorial: Wirelessly Powered Networks, And Technologies, Theofanis P. Raptis, Nuno B. Carvalho, Diego Masotti, Lei Shu, Cong Wang, Yuanyuan Yang

Computer Science Faculty Publications

Wireless Power Transfer (WPT) is, by definition, a process that occurs in any system where electrical energy is transmitted from a power source to a load without the connection of electrical conductors. WPT is the driving technology that will enable the next stage in the current consumer electronics revolution, including battery-less sensors, passive RF identification (RFID), passive wireless sensors, the Internet of Things and 5G, and machine-to-machine solutions. WPT-enabled devices can be powered by harvesting energy from the surroundings, including electromagnetic (EM) energy, leading to a new communication networks paradigm, the Wirelessly Powered Networks.


A Survey Of Attention Deficit Hyperactivity Disorder Identification Using Psychophysiological Data, S. De Silva, S. Dayarathna, G. Ariyarathne, D. Meedeniya, Sampath Jayarathna Jan 2019

A Survey Of Attention Deficit Hyperactivity Disorder Identification Using Psychophysiological Data, S. De Silva, S. Dayarathna, G. Ariyarathne, D. Meedeniya, Sampath Jayarathna

Computer Science Faculty Publications

Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common neurological disorders among children, that affects different areas in the brain that allows executing certain functionalities. This may lead to a variety of impairments such as difficulties in paying attention or focusing, controlling impulsive behaviours and overreacting. The continuous symptoms may have a severe impact in the long-term. This paper explores the ADHD identification studies using eye movement data and functional Magnetic Resonance Imaging (fMRI). This study discusses different machine learning techniques, existing models and analyses the existing literature. We have identified the current challenges and possible future directions …


Sec-Lib: Protecting Scholarly Digital Libraries From Infected Papers Using Active Machine Learning Framework, Nir Nissim, Aviad Cohen, Jian Wu, Andrea Lanzi, Lior Rokach, Yuval Elovici, Lee Giles Jan 2019

Sec-Lib: Protecting Scholarly Digital Libraries From Infected Papers Using Active Machine Learning Framework, Nir Nissim, Aviad Cohen, Jian Wu, Andrea Lanzi, Lior Rokach, Yuval Elovici, Lee Giles

Computer Science Faculty Publications

Researchers from academia and the corporate-sector rely on scholarly digital libraries to access articles. Attackers take advantage of innocent users who consider the articles' files safe and thus open PDF-files with little concern. In addition, researchers consider scholarly libraries a reliable, trusted, and untainted corpus of papers. For these reasons, scholarly digital libraries are an attractive-target and inadvertently support the proliferation of cyber-attacks launched via malicious PDF-files. In this study, we present related vulnerabilities and malware distribution approaches that exploit the vulnerabilities of scholarly digital libraries. We evaluated over two-million scholarly papers in the CiteSeerX library and found the library …


Eeg-Based Processing And Classification Methodologies For Autism Spectrum Disorder: A Review, Gunavaran Brihadiswaran, Dilantha Haputhanthri, Sahan Gunathilaka, Dulani Meedeniya, Sampath Jayarathna Jan 2019

Eeg-Based Processing And Classification Methodologies For Autism Spectrum Disorder: A Review, Gunavaran Brihadiswaran, Dilantha Haputhanthri, Sahan Gunathilaka, Dulani Meedeniya, Sampath Jayarathna

Computer Science Faculty Publications

Autism Spectrum Disorder is a lifelong neurodevelopmental condition which affects social interaction, communication and behaviour of an individual. The symptoms are diverse with different levels of severity. Recent studies have revealed that early intervention is highly effective for improving the condition. However, current ASD diagnostic criteria are subjective which makes early diagnosis challenging, due to the unavailability of well-defined medical tests to diagnose ASD. Over the years, several objective measures utilizing abnormalities found in EEG signals and statistical analysis have been proposed. Machine learning based approaches provide more flexibility and have produced better results in ASD classification. This paper presents …


Clinical Big Data And Deep Learning: Applications, Challenges, And Future Outlooks, Ying Yu, Liangliang Liu, Yaohang Li, Jianxin Wang Jan 2019

Clinical Big Data And Deep Learning: Applications, Challenges, And Future Outlooks, Ying Yu, Liangliang Liu, Yaohang Li, Jianxin Wang

Computer Science Faculty Publications

The explosion of digital healthcare data has led to a surge of data-driven medical research based on machine learning. In recent years, as a powerful technique for big data, deep learning has gained a central position in machine learning circles for its great advantages in feature representation and pattern recognition. This article presents a comprehensive overview of studies that employ deep learning methods to deal with clinical data. Firstly, based on the analysis of the characteristics of clinical data, various types of clinical data (e.g., medical images, clinical notes, lab results, vital signs and demographic informatics) are discussed and details …


Electroencephalogram (Eeg) For Delineating Objective Measure Of Autism Spectrum Disorder, Sampath Jayarathna, Yasith Jayawardana, Mark Jaime, Sashi Thapaliya Jan 2019

Electroencephalogram (Eeg) For Delineating Objective Measure Of Autism Spectrum Disorder, Sampath Jayarathna, Yasith Jayawardana, Mark Jaime, Sashi Thapaliya

Computer Science Faculty Publications

Autism spectrum disorder (ASD) is a developmental disorder that often impairs a child's normal development of the brain. According to CDC, it is estimated that 1 in 6 children in the US suffer from development disorders, and 1 in 68 children in the US suffer from ASD. This condition has a negative impact on a person's ability to hear, socialize, and communicate. Subjective measures often take more time, resources, and have false positives or false negatives. There is a need for efficient objective measures that can help in diagnosing this disease early as possible with less effort. EEG measures the …


Multi-View Cluster Analysis With Incomplete Data To Understand Treatment Effects, Guoqing Chao, Jiangwen Sun, Jin Lu, An-Li Wang, Daniel D. Langleben, Chiang-Shan Li, Jinbo Bi Jan 2019

Multi-View Cluster Analysis With Incomplete Data To Understand Treatment Effects, Guoqing Chao, Jiangwen Sun, Jin Lu, An-Li Wang, Daniel D. Langleben, Chiang-Shan Li, Jinbo Bi

Computer Science Faculty Publications

Multi-view cluster analysis, as a popular granular computing method, aims to partition sample subjects into consistent clusters across different views in which the subjects are characterized. Frequently, data entries can be missing from some of the views. The latest multi-view co-clustering methods cannot effectively deal with incomplete data, especially when there are mixed patterns of missing values. We propose an enhanced formulation for a family of multi-view co-clustering methods to cope with the missing data problem by introducing an indicator matrix whose elements indicate which data entries are observed and assessing cluster validity only on observed entries. In comparison with …


Drug Repositioning Based On Bounded Nuclear Norm Regularization, Mengyun Yang, Huimin Lao, Yaohang Li, Jianxin Wang Jan 2019

Drug Repositioning Based On Bounded Nuclear Norm Regularization, Mengyun Yang, Huimin Lao, Yaohang Li, Jianxin Wang

Computer Science Faculty Publications

Motivation: Computational drug repositioning is a cost-effective strategy to identify novel indications for existing drugs. Drug repositioning is often modeled as a recommendation system problem. Taking advantage of the known drug–disease associations, the objective of the recommendation system is to identify new treatments by filling out the unknown entries in the drug–disease association matrix, which is known as matrix completion. Underpinned by the fact that common molecular pathways contribute to many different diseases, the recommendation system assumes that the underlying latent factors determining drug–disease associations are highly correlated. In other words, the drug–disease matrix to be completed is low-rank. Accordingly, …


Automatic Slide Generation For Scientific Papers, Athar Sefid, Jian Wu, Prasenjit Mitra, C. Lee Giles Jan 2019

Automatic Slide Generation For Scientific Papers, Athar Sefid, Jian Wu, Prasenjit Mitra, C. Lee Giles

Computer Science Faculty Publications

We describe our approach for automatically generating presentation slides for scientific papers using deep neural networks. Such slides can help authors have a starting point for their slide generation process. Extractive summarization techniques are applied to rank and select important sentences from the original document. Previous work identified important sentences based only on a limited number of features that were extracted from the position and structure of sentences in the paper. Our method extends previous work by (1) extracting a more comprehensive list of surface features, (2) considering semantic or meaning of the sentence, and (3) using context around the …


Web Archives At The Nexus Of Good Fakes And Flawed Originals, Michael L. Nelson Jan 2019

Web Archives At The Nexus Of Good Fakes And Flawed Originals, Michael L. Nelson

Computer Science Faculty Publications

[Summary] The authenticity, integrity, and provenance of resources we encounter on the web are increasingly in question. While many people are inured to the possibility of altered images, the easy accessibility of powerful software tools that synthesize audio and video will unleash a torrent of convincing “deepfakes” into our social discourse. Archives will no longer be monopolized by a countable number of institutions such as governments and publishers, but will become a competitive space filled with social engineers, propagandists, conspiracy theorists, and aspiring Hollywood directors. While the historical record has never been singular nor unmalleable, current technologies empower an unprecedented …