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A Bioinformatics Framework For Rna Structure Mining, Motif Discovery And Polyadenylation Analysis, Mugdha Khaladkar
A Bioinformatics Framework For Rna Structure Mining, Motif Discovery And Polyadenylation Analysis, Mugdha Khaladkar
Dissertations
The RNA molecules play various important roles in the cell and their functionality depends not only on the sequence information but to a large extent on their structure. The development of computational and predictive approaches to study RNA molecules is extremely valuable. In this research, a tool named RADAR was developed that provides a multitude of functionality for RNA data analysis and research. It aligns structure annotated RNA sequences so that both the sequence as well as structure information is taken into consideration. This tool is capable of performing pair-wise structure alignment, multiple structure alignment, database search and clustering. In …