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Full-Text Articles in Physical Sciences and Mathematics
Specification For Visual Requirements Of Work-Centered Software Systems, James Robert Knapp
Specification For Visual Requirements Of Work-Centered Software Systems, James Robert Knapp
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Work-centered software systems function as inherent work-aiding systems. Based on the design concept for a work-centered support system (WCSS), these software systems support user tasks and goals through both direct and indirect aiding methods within the interface client. In order to ensure the coherent development and delivery of work-centered software products, WCSS visual interface requirements must be specified in order to capture the cognitive and work-aiding aspects of the user interface design. Without the ability to specify such original requirements, the probability of creating an accurate and effective work-centered software system is significantly reduced. A new visual requirements specification language …
A Computational Framework For Analyzing Chemical Modification And Limited Proteolysis Experimental Data Used For High Confidence Protein Structure Prediction, Paul E. Anderson
A Computational Framework For Analyzing Chemical Modification And Limited Proteolysis Experimental Data Used For High Confidence Protein Structure Prediction, Paul E. Anderson
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Prediction of protein tertiary structure based on amino acid sequence is one of the most challenging open questions in computational molecular biology. Experimental methods for protein structure determination remain relatively time consuming and expensive, and are not applicable to all proteins. While a diverse array of algorithms have been developed for prediction of protein structure from amino acid sequence information, the accuracy and reliability of these methods are not yet comparable to experimental structure determination techniques. Computational models of protein structure can, however, be improved by the incorporation of experimental information. Relatively rapid and inexpensive protein modification experiments can be …