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Full-Text Articles in Physical Sciences and Mathematics
Integrative Pathway Analysis Pipeline For Mirna And Mrna Data, Diana Mabel Diaz Herrera
Integrative Pathway Analysis Pipeline For Mirna And Mrna Data, Diana Mabel Diaz Herrera
Wayne State University Theses
The identification of pathways that are involved in a particular phenotype helps us understand the underlying biological processes. Traditional pathway analysis techniques aim to infer the impact on individual pathways using only mRNA levels. However, recent studies showed that gene expression alone is unable to capture the whole picture of biological phenomena. At the same time, MicroRNAs (miRNAs) are newly discovered gene regulators that have shown to play an important role in diagnosis, and prognosis for different types of diseases. Current pathway analysis techniques do not take miRNAs into consideration. In this project, we investigate the effect of integrating miRNA …
Medical Data Analysis Method For Epilepsy, Ameen Eetemadi
Medical Data Analysis Method For Epilepsy, Ameen Eetemadi
Wayne State University Theses
Applying data mining techniques on medical databases which contain un-structured and semi-structured data is a challenging task. It is not only due to the complexity of such databases but also due to the characteristics of the medical domain. This thesis describes how multiple layers of data mining techniques have been applied to a Human Brain Image Database system. It starts with data preparation which paves the way for conventional data analysis techniques to be applied to the data. A similarity based patient retrieval tool has been designed and developed to assist in treatment planning and outcome estimation for epileptic patients. …