Physical Sciences and Mathematics Commons^™

Algorithmic Fusion Of Gene Expression Profiling For Diffuse Large B-Cell Lymphoma Outcome Prediction, Qiuming Zhu, Hongmei Cui, Kahai Cao, Wing C. Chan

Computer Science Faculty Publications

Many different methods and techniques have been investigated for the processing and analysis of microarray gene expression profiling datasets. It is noted that the accuracy and reliability of the results are often dependent on the measurement approaches applied, and no single measurement so far is guaranteed to generate a satisfactory result. In this paper, an algorithmic fusion approach is presented for extracting genes that are predictive to clinical outcomes (survival-fatal) of diffuse large B-cell lymphoma on a set of microarray data for gene expression profiling. The approach integrates a set of measurements from different aspects in terms of the discrepancy …