Physical Sciences and Mathematics Commons^™

Enhancing Timeliness Of Drug Overdose Mortality Surveillance: A Machine Learning Approach, Patrick J. Ward, Peter J. Rock, Svetla Slavova, April M. Young, Terry L. Bunn, Ramakanth Kavuluru

Kentucky Injury Prevention and Research Center Faculty Publications

BACKGROUND: Timely data is key to effective public health responses to epidemics. Drug overdose deaths are identified in surveillance systems through ICD-10 codes present on death certificates. ICD-10 coding takes time, but free-text information is available on death certificates prior to ICD-10 coding. The objective of this study was to develop a machine learning method to classify free-text death certificates as drug overdoses to provide faster drug overdose mortality surveillance.

METHODS: Using 2017–2018 Kentucky death certificate data, free-text fields were tokenized and features were created from these tokens using natural language processing (NLP). Word, bigram, and trigram features were created …

Influence Spread In Two-Layer Interdependent Networks: Designed Single-Layer Or Random Two-Layer Initial Spreaders?, Hana Khamfroush, Nathaniel Hudson, Samuel Iloo, Mahshid R. Naeini

Computer Science Faculty Publications

Influence spread in multi-layer interdependent networks (M-IDN) has been studied in the last few years; however, prior works mostly focused on the spread that is initiated in a single layer of an M-IDN. In real world scenarios, influence spread can happen concurrently among many or all components making up the topology of an M-IDN. This paper investigates the effectiveness of different influence spread strategies in M-IDNs by providing a comprehensive analysis of the time evolution of influence propagation given different initial spreader strategies. For this study we consider a two-layer interdependent network and a general probabilistic threshold influence spread model …

From Invisibility To Readability: Recovering The Ink Of Herculaneum, Clifford Seth Parker, Stephen Parsons, Jack Bandy, Christy Chapman, Frederik Coppens, William Brent Seales

Computer Science Faculty Publications

The noninvasive digital restoration of ancient texts written in carbon black ink and hidden inside artifacts has proven elusive, even with advanced imaging techniques like x-ray-based micro-computed tomography (micro-CT). This paper identifies a crucial mistaken assumption: that micro-CT data fails to capture any information representing the presence of carbon ink. Instead, we show new experiments indicating a subtle but detectable signature from carbon ink in micro-CT. We demonstrate a new computational approach that captures, enhances, and makes visible the characteristic signature created by carbon ink in micro-CT. This previously "unseen" evidence of carbon inks, which can now successfully be made …

Sensitive Research, Practice And Design In Hci, Stevie Chancellor, Nazanin Andalibi, Lindsay Blackwell, David Nemer, Wendy Moncur

Information Science Faculty Publications

New research areas in HCI examine complex and sensitive research areas, such as crisis, life transitions, and mental health. Further, research in complex topics such as harassment and graphic content can leave researchers vulnerable to emotional and physical harm. There is a need to bring researchers together to discuss challenges across sensitive research spaces and environments. We propose a workshop to explore the methodological, ethical, and emotional challenges of sensitive research in HCI. We will actively recruit from diverse research environments (industry, academia, government, etc.) and methods areas (qualitative, quantitative, design practices, etc.) and identify commonalities in and encourage relationship-building …

A Generative Human-Robot Motion Retargeting Approach Using A Single Rgbd Sensor, Sen Wang, Xinxin Zuo, Runxiao Wang, Ruigang Yang

Computer Science Faculty Publications

The goal of human-robot motion retargeting is to let a robot follow the movements performed by a human subject. Typically in previous approaches, the human poses are precomputed from a human pose tracking system, after which the explicit joint mapping strategies are specified to apply the estimated poses to a target robot. However, there is not any generic mapping strategy that we can use to map the human joint to robots with different kinds of configurations. In this paper, we present a novel motion retargeting approach that combines the human pose estimation and the motion retargeting procedure in a unified …

Examining Medline Search Query Reproducibility And Resulting Variation In Search Results, C. Sean Burns, Robert M. Shapiro Ii, Tyler Nix, Jeffrey T. Huber

Information Science Faculty Publications

The MEDLINE database is publicly available through the National Library of Medicine’s PubMed but the data file itself is also licensed to a number of vendors, who may offer their versions to institutional and other parties as part of a database platform. These vendors provide their own interface to the MEDLINE file and offer other technologies that attempt to make their version useful to subscribers. However, little is known about how vendor platforms ingest and interact with MEDLINE data files, nor how these changes influence the construction of search queries and the results they produce. This poster presents a longitudinal …

Overview Of The Biocreative Vi Precision Medicine Track: Mining Protein Interactions And Mutations For Precision Medicine, Rezarta Islamaj Doğan, Sun Kim, Andrew Chatr-Aryamontri, Chih-Hsuan Wei, Donald C. Comeau, Rui Antunes, Sérgio Matos, Qingyu Chen, Aparna Elangovan, Nagesh C. Panyam, Karin Verspoor, Hongfang Liu, Yanshan Wang, Zhuang Liu, Berna Altınel, Zehra Melce Hüsünbeyi, Arzucan Özgür, Aris Fergadis, Chen-Kai Wang, Hong-Jie Dai, Tung Tran, Ramakanth Kavuluru, Ling Luo, Albert Steppi, Jinfeng Zhang, Jinchan Qu, Zhiyong Lu

Computer Science Faculty Publications

The Precision Medicine Initiative is a multicenter effort aiming at formulating personalized treatments leveraging on individual patient data (clinical, genome sequence and functional genomic data) together with the information in large knowledge bases (KBs) that integrate genome annotation, disease association studies, electronic health records and other data types. The biomedical literature provides a rich foundation for populating these KBs, reporting genetic and molecular interactions that provide the scaffold for the cellular regulatory systems and detailing the influence of genetic variants in these interactions. The goal of BioCreative VI Precision Medicine Track was to extract this particular type of information and …

Walking With A Robotic Exoskeleton Does Not Mimic Natural Gait: A Within-Subjects Study, Chad Swank, Sharon Wang-Price, Fan Gao, Sattam Almutairi

Kinesiology and Health Promotion Faculty Publications

Background: Robotic exoskeleton devices enable individuals with lower extremity weakness to stand up and walk over ground with full weight-bearing and reciprocal gait. Limited information is available on how a robotic exoskeleton affects gait characteristics.

Objective: The purpose of this study was to examine whether wearing a robotic exoskeleton affects temporospatial parameters, kinematics, and muscle activity during gait.

Methods: The study was completed by 15 healthy adults (mean age 26.2 [SD 8.3] years; 6 males, 9 females). Each participant performed walking under 2 conditions: with and without wearing a robotic exoskeleton (EKSO). A 10-camera motion analysis system synchronized with 6 …