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Physical Sciences and Mathematics Commons™

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Computer Sciences

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Wright State University

2017

Clustering

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Full-Text Articles in Physical Sciences and Mathematics

A Novel Approach For Classifying Gene Expression Data Using Topic Modeling, Soon Jye Kho, Himi Yalamanchili, Michael L. Raymer, Amit Sheth Jan 2017

A Novel Approach For Classifying Gene Expression Data Using Topic Modeling, Soon Jye Kho, Himi Yalamanchili, Michael L. Raymer, Amit Sheth

Kno.e.sis Publications

Understanding the role of differential gene expression in cancer etiology and cellular process is a complex problem that continues to pose a challenge due to sheer number of genes and inter-related biological processes involved. In this paper, we employ an unsupervised topic model, Latent Dirichlet Allocation (LDA) to mitigate overfitting of high-dimensionality gene expression data and to facilitate understanding of the associated pathways. LDA has been recently applied for clustering and exploring genomic data but not for classification and prediction. Here, we proposed to use LDA inclustering as well as in classification of cancer and healthy tissues using lung cancer …

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Semantics-Based Summarization Of Entities In Knowledge Graphs, Kalpa Gunaratna Jan 2017

Semantics-Based Summarization Of Entities In Knowledge Graphs, Kalpa Gunaratna

Browse all Theses and Dissertations

The processing of structured and semi-structured content on the Web has been gaining attention with the rapid progress in the Linking Open Data project and the development of commercial knowledge graphs. Knowledge graphs capture domain-specific or encyclopedic knowledge in the form of a data layer and add rich and explicit semantics on top of the data layer to infer additional knowledge. The data layer of a knowledge graph represents entities and their descriptions. The semantic layer on top of the data layer is called the schema (ontology), where relationships of the entity descriptions, their classes, and the hierarchy of the …

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