Physical Sciences and Mathematics Commons^™

Picolinyl-Assisted Approaches To Stereocontrolled Glycosylation, Jagodige Prithika Yasomanee

Dissertations

Although carbohydrates are the most abundant molecules on Earth, our current knowledge of these fascinating natural compounds is still limited. Some aspects that are already known include the carbohydrate involvement in damaging cellular processes such as bacterial and viral infections, development of tumors, metastasis, septic shock, etc. Consequently the development of effective methods for the synthesis, isolation, analysis, and investigation of complex carbohydrates has become critical in all areas of glycoscience. Among various focus areas, stereocontrolled glycosylation has emerged as a topic of particular importance. Yet, it remains a remarkable challenge to chemists because a new chirality center is formed …