Physical Sciences and Mathematics Commons^™

Synthesis And Temperature-Induced Phase Transfer Behavior Of Thermosensitive Hairy Particles Between Aqueous Solution And A Hydrophobic Ionic Liquid, Jonathan Michael Horton

Doctoral Dissertations

This dissertation presents the synthesis of a family of thermosensitive polymer brush-grafted silica particles and the study of their thermally induced phase transfer behavior between water and a hydrophobic ionic liquid, 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)amide ([EMIM][TFSA]). The hairy particles were prepared by surface-initiated atom transfer radical polymerization.

Chapter 1 describes the synthesis and phase transfer behavior of a series of 205 nm silica particles grafted with thermosensitive polymers of methoxyoligo(ethylene glycol) methacrylates. The hairy particles with sufficiently high lower critical solution temperatures underwent reversible and quantitative transfer between water and [EMIM][TFSA] in response to temperature changes. The transfer temperature (T_{tr …}

Synthesis Of Self-Immolative Monomers And Their Applications In Polymeric Materials, Matthew A. Dewit

Electronic Thesis and Dissertation Repository

Self-immolative spacers are a unique class of molecules employed in a variety of applications, particularly in the biomedical field. Most commonly, they are molecules containing two reactive termini with a capping group at one terminus and a substrate of interest at the other. Upon removal of the capping group, the spacer undergoes an intramolecular reaction that results in its removal from the molecule and liberation of the substrate. These spacers have been extensively studied in monomeric form within prodrugs, as well as to form dendrimers that have been used for applications such as signal amplification, molecular logic gates and amplified …