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The Synthesis Of Methyl-2-Acetamido-3,4,6-0-Triacetyl Alpha-D-Talosaminide, Mohammad Saleem Choudhary
The Synthesis Of Methyl-2-Acetamido-3,4,6-0-Triacetyl Alpha-D-Talosaminide, Mohammad Saleem Choudhary
University of the Pacific Theses and Dissertations
Amongst the very many different kinds of amino sugars, theones that have aroused the most interest are the 2-amino 2-deoxy hexoses which are found in such well known antibiotics as streptomycin and neomycine (2). There are so far about forty-three antibiotics which are known to contain different aminosugars (6).
Aminosugars exhibit the same properties as other reducing aldohexoses, e. g. reduction of silver and cupric salts, oxidation to hexonic acids, reduction to alcohols and formation of glycosides.
The object of this project is to synthesize methyl N-acetyl α-D-talosaminide which has previously been prepared by Jeanloz (3) following a different route. …