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Physical Sciences and Mathematics Commons

Open Access. Powered by Scholars. Published by Universities.®

Chemistry

Research outputs 2014 to 2021

2018

Mass spectrometry

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Full-Text Articles in Physical Sciences and Mathematics

Guidelines And Considerations For The Use Of System Suitability And Quality Control Samples In Mass Spectrometry Assays Applied In Untargeted Clinical Metabolomic Studies, David Broadhurst, Royston Goodacre, Stacey N. Reinke, Julia Kuligowski, Ian Wilson, Matthew Lewis, Warwick Dunn Jan 2018

Guidelines And Considerations For The Use Of System Suitability And Quality Control Samples In Mass Spectrometry Assays Applied In Untargeted Clinical Metabolomic Studies, David Broadhurst, Royston Goodacre, Stacey N. Reinke, Julia Kuligowski, Ian Wilson, Matthew Lewis, Warwick Dunn

Research outputs 2014 to 2021

Background

Quality assurance (QA) and quality control (QC) are two quality management processes that are integral to the success of metabolomics including their application for the acquisition of high quality data in any high-throughput analytical chemistry laboratory. QA defines all the planned and systematic activities implemented before samples are collected, to provide confidence that a subsequent analytical process will fulfil predetermined requirements for quality. QC can be defined as the operational techniques and activities used to measure and report these quality requirements after data acquisition.

Aim of review

This tutorial review will guide the reader through the use of system …