Physical Sciences and Mathematics Commons^™

In-Vivo Delivery Of Dna Vaccines Using Metallo-Lipid Nanoparticles, Clarissa Sara Gomez

Open Access Theses & Dissertations

There has been a rapidly growing area of research in the design and synthesis of molecules that self-organize in water to form functional nanosystems and due to the high interest in the area metal ligand complexes were tested as drug delivery systems with a Leishmania vaccine. Herein, we present the design, synthesis and functional activity of Cu(II) and Zn(II) complexes that self-assemble in water to form spherical nanoscale structures that exhibit an affinity to bind DNA and deliver it into eukaryotic cells with a high percent efficiency in-vitro. In order to assess the effectiveness of these nanoparticles to deliver DNA …

Optical And Vibrational Spectroscopic Studies Of Synthetic Maya Pigments As A Function Of, Swati Kumar

Open Access Theses & Dissertations

Pigments developed by the Mayan civilization around 8th century, represent some of the most versatile pigments known to date. Several derivatives of these pigments are popular subjects of current research interest. This is due to the characteristic stability which is provided by a bonding mechanism between the dye and the clay. One such pigment "Maya Blue", a mixture of Indigo and Palygorskite, provides a dramatic background for murals and ceramics throughout Mesoamerica. Several research groups have devoted time and interest in unlocking its particular features.1-3

The work embodied in this Thesis is focused on the synThesis and characterization of three …

A Study Of The Interaction Of Thioindigo Dye, With Several Inorganic Host Materials, Alejandra Ramirez

Open Access Theses & Dissertations

Maya Blue has been the focus of numerous studies and is believed to be a mixture of palygorskite clay and indigo dye.^1,2 Several derivatives of this pigment have been developed with intriguing properties. For instance, the dye thioindigo reacts with the palygorskite clay to exhibit a broad range of colors from red to blue under UV-Vis excitation. Based on FT-Raman and computer simulation, previous work performed in our group could relate indigo and thioindigo interaction to the aluminum sites in the framework. super>3,4

The work performed with other inorganic host materials such as, layer structures and zeolites have …