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Full-Text Articles in Physical Sciences and Mathematics
Recent Studies On The Synthesis Of Medicinal Molecules., Paige Monsen
Recent Studies On The Synthesis Of Medicinal Molecules., Paige Monsen
Electronic Theses and Dissertations
Medicinal chemistry interfaces synthetic organic chemistry, natural product chemistry and chemical biology, with a goal of yielding therapeutic agents. Natural products or compounds derived from natural sources such as plants, animals, and microorganisms, are often biologically active and render that compound a likely drug lead. For thousands of years humankind has utilized natural products for medicinal purposes and consequently scientists take advantage of both these compounds’ core structural characteristics and their modes of actions on selected targets as inspiration to develop therapeutics. Because the total synthesis of such complex molecules can be cumbersome and expensive, semi-synthetic methods on isolated natural …
Novel Acetylcholine Chloride Based Water Immiscible Deep Eutectic Solvent: Formulation, Characterization And Application In Drug Solubilization, Shiksha Subedi
Novel Acetylcholine Chloride Based Water Immiscible Deep Eutectic Solvent: Formulation, Characterization And Application In Drug Solubilization, Shiksha Subedi
Electronic Theses and Dissertations
Deep eutectic solvents (DESs) are the emerging class of new and inexpensive solvents composed of two or three safe components capable of self-association through hydrogen bond interaction. The depression in the melting point characterizes DESs compared to those of the individual components. These solvents have properties like the traditionally used ionic liquids (ILs), but they can offset the significant drawbacks of ILs, such as biodegradability, toxicity, and complex synthesis. Due to these remarkable advantages, the research in DESs is increasing exponentially. However, current deep eutectic solvents still have limitations to apply to the real chemical industries due to hydrophilicity and …