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Full-Text Articles in Physical Sciences and Mathematics
Effects Of Arsenic And Uvb Radiation On Induction Of Cyclin D1 In Human Keratinocytes., Julian Gonzalez
Effects Of Arsenic And Uvb Radiation On Induction Of Cyclin D1 In Human Keratinocytes., Julian Gonzalez
Dissertations and Theses
Arsenic and Ultraviolet radiation B (UVB) are environmental toxins that have been linked to various epithelial cancers. Arsenic metabolism in humans leads to its collection in the skin, where it encounters and can act with known carcinogen UVB. Epidemiological evidence of the two toxins demonstrates their potential to affect signaling pathways, with various consequences. Here we employ an in vitro model system using Normal Human Epidermal Keratinocytes (NHEK) to identify the effect of arsenic and UVB on humans and whether they work synergistically. We find that although both cause induction of cyclin D1, culturing cells with both co-mutagens does not …
The Development Of An Arsenic(V) Selective Electrode, Sandra Gee Kang
The Development Of An Arsenic(V) Selective Electrode, Sandra Gee Kang
Dissertations and Theses
The object of this research was to develop an arsenic(V) selective electrode. The electrode is based on a solid state membrane prepared by pressing a precipitate of silver arsenate-silver sulfide into a pellet. After the electrode was made, experiments were designed to check for three general characteristics of the electrodes: dependence of potential on pH for constant arsenic(V) concentration; dependence of potential on arsenic(V) concentrations at constant pH and extent of interference due to phosphate and arsenic(III) ions. From these measurements, it was found that Ag2HAs04 was formed originally in the membranes containing a small fraction of …