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Physical Sciences and Mathematics Commons

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Chemistry

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

2014

Poly(A)recognition

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Full-Text Articles in Physical Sciences and Mathematics

Detailed Analysis Of The Domains Of Mtr4 And How They Regulate Helicase Activity, Lacy Leigh Taylor May 2014

Detailed Analysis Of The Domains Of Mtr4 And How They Regulate Helicase Activity, Lacy Leigh Taylor

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The central dogma states that DNA is transcribed into RNA, which is then translated into protein. This concept conveys a minimal view of the role of RNA, portraying it simply as an intermediary between DNA and protein. However, it is now known that the role of RNA in the cell is critical in regulating protein expression both directly and indirectly. RNA in the cell typically goes through modifications to become active (on) and inactive (off) to eventually become targeted for degradation and start the cycle all over again. The protein complex that regulates the proper maturation and degradation of RNA …