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Physical Sciences and Mathematics Commons

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Chemistry

Utah State University

Theses/Dissertations

2012

Structure

Articles 1 - 2 of 2

Full-Text Articles in Physical Sciences and Mathematics

Rationalizing Structure, Stability, And Chemical Bonding Of Pure And Doped Clusters Isolated And Solvated Multiply Charged Anions, And Solid State Materials, Alina P. Sergeeva May 2012

Rationalizing Structure, Stability, And Chemical Bonding Of Pure And Doped Clusters Isolated And Solvated Multiply Charged Anions, And Solid State Materials, Alina P. Sergeeva

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Chemistry is the study of materials and the changes that materials undergo. One can tune the properties of the known materials and design the novel materials with desired properties knowing what is responsible for the chemical reactivity, structure, and stability of those materials. The unified chemical bonding theory could address all these questions, but we do not have one available yet. The most accepted general theory of chemical bonding was proposed by Lewis in 1916, though Lewis’s theory fails to explain the bonding in materials with delocalized electron density such as sub-nano and nanoclusters, as well as aromatic organic and …


Structural And Functional Characterization Of The Essential Rna Helicase Mtr4, Ryan N. Jackson May 2012

Structural And Functional Characterization Of The Essential Rna Helicase Mtr4, Ryan N. Jackson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

To insure the integrity of nuclear RNA, the eukaryotic cell employs surveillance systems that identify and degrade RNAs that are detrimental or unneeded. The failure of RNA surveillance systems can lead to neurodegenerative disease states and cancer. The essential RNA helicase Mtr4 is required for the degradation and processing of several nuclear RNAs. To further the understanding of RNA surveillance and processing in eukaryotes, Ryan Jackson of the Department of Chemistry and Biochemistry at Utah State University has determined the molecular structure of Mtr4 and has used this structure to interrogate Mtr4 function biochemically. The structure revealed that Mtr4 contains …