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Physical Sciences and Mathematics Commons™
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Full-Text Articles in Physical Sciences and Mathematics
I. The Synthesis And Coordination Chemistry Of Novel 6n-Electron Ligands. Ii. Improvement Of Student Writing Skills In Chemistry Lab Reports Through The Use Of Calibrated Peer Review, Wilson William
Chemistry and Chemical Biology ETDs
ABSTRACT I: The goal of this study was to synthesize and characterize a set of coordination complexes containing 6pi-cationic ligands. These compounds could be extremely useful as catalysts for the polymerization of olefins that are widely used in the synthetic polymer industry. The original strategy was to synthesize the 6pi-cationic ligands using (Ph2P)3CH (1) and (Me2P)3CH (10) as precursors; however, both precursors 1 and 10 were found to be highly reactive leading to the fragmentation products (Ph2P)2CH2 and (Me2P)2CH2 respectively. In trying to control the reactivity, precursor 1 was coordinated to the group 6B metal carbonyl in two modes, Mo(CO)3(C2H5CN)(Ph2P)2CHPPh2 …
Mechanistic Studies On Xanthine Oxidoreductase Enzymes, Abebe Berhane
Mechanistic Studies On Xanthine Oxidoreductase Enzymes, Abebe Berhane
Chemistry and Chemical Biology ETDs
In humans, the xanthine oxidoreductase enzymes are known to catalyze the final two steps of purine metabolism by converting hypoxanthine successively to xanthine and uric acid. Xanthine oxidoreductase also metabolizes a wide variety of drugs in vivo, and activates a number of antiviral prodrugs of clinical importance. Therefore, understanding the reaction mechanism of this enzyme is of prime importance in furthering our understanding of enzyme-drug interactions. In order to provide a greater understanding on the reaction mechanism, theoretical and enzymatic spectroscopic experimental approaches have been utilized. The theoretical approaches were used to elucidate the electronic structure and geometry of the …
Investigations Into Late Transition Metal Pincer Complexes As Possible Direct Partial Oxidation Catalysts, Raymond B. Lansing Jr
Investigations Into Late Transition Metal Pincer Complexes As Possible Direct Partial Oxidation Catalysts, Raymond B. Lansing Jr
Chemistry and Chemical Biology ETDs
This investigation examined aspects of a potential catalytic route for the partial oxidation of organic substrates using molecular oxygen as the oxidant. The proposed cycle begins with the insertion of molecular oxygen into a metal hydride bond to generate a metal hydroperoxide. The next step involves the transfer of an oxygen atom to an acceptor substrate to generate an oxidized species and a metal hydroxide. The starting metal hydride can then be regenerated in two viable ways, either through use of CO or H2. The experimental plan involved the syntheses and characterization of new inorganic and organometallic complexes, and it …